Assessing relationships between health-related quality of life and adherence to antiretroviral therapy

Abstract

HRQoL dimensions, notably cognitive functioning, financial status and medical care, are closely associated with antiretroviral therapy adherence.

Barriers to Adherence to Antiretroviral Treatment Among Inmates of a Prison in Tehran, Iran: A Qualitative Study

“…Optimal adherence to medication regimen is a crucial factor to obtain desirable clinical outcomes in patients with HIV (1, 2), while suboptimal adherence results in poor clinical outcomes (3,4), poor quality of life (5,6), and mortality (7).…”

Factors Associated with Non-Adherence to Antiretroviral Therapy among Adults living with HIV/AIDS in Arsi Zone, Oromia

“…Non adherence to antiretroviral therapy has been associated to diverse factors including patient related factors, health condition/disease, health care system/ health care team, therapy/treatment and socio-economic factors [20][21][22]. Reasons for non-adherence are multi factorial.…”

Social Position as a Structural Determinant of Adherence to Treatment in Women Living with HIV/AIDS

“…A systematic literature review of 116 studies presents the conclusion that even though there is a positive trend in relation to adherence in various chronic illnesses and some areas of socioeconomic status, for example income, education and occupation, there is insufficient evidence about statistically significant associations between socioeconomic status and adherence among patients with HIV/AIDS (Falagas, 2008). On the contrary, other studies carried out with men and women reveal associations between a deficient financial situation and non-adherence (Carballo et al, 2004;Castro, 2005;Chesney, Chesney et al, 2000;Gifford et al, 2000;Glass, et al, 2006;Gordillo, 1999;Ickovics & Meade, 2002;Kleeberger et al, 2001). The truth is that poverty accounts for a higher probability of social disadvantages associated with risks to adherence.…”

“…Allied to the other conditions which are typical of the lives of poor HIV-positive women, low education level can trigger a bad prognosis and the high risk of death from AIDS. With respect to income level, some authors have suggested that there are associations with adherence (Carballo et al, 2004;Ickovics & Meade, 2002), and propose that it would be reasonable to argue that attention to basic needs is more beneficial than direct attention to adherence. In particular, women of a low social position could receive social support for the satisfaction of their basic needs.…”

“…Much of the research on HIV/AIDS adherence has been rooted in biomedical and behavioral approaches. Studied variables include age, gender, education (Carballo et al, 2004;Glass et al, 2006;Godin et al, 2005;Gordillo et al,1999;Ickovics & Meade, 2002;Mocroft et al, 2001;Spire et al, 2002;Sternhell & Corr, 2002), health beliefs, coping styles, self-efficacy, control perception, stress, anxiety, depression (Chesney, 2000;Ingersoll, 2004;Turner-Cobb et al, 2002), pharmacological regimen, side effects, relationship with health care providers, geographical barriers, and social support (Burke et al, 2003;Chesney, Morin & Sherr, 2000). Despite wide research on this topic, studies have not reach conceptual explanations about the relation between adherence to treatment in people diagnosed with HIV and structural determinants such as social position.…”