Assessing psychological factors, social aspects and psychiatric co-morbidity associated with Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS) in men — A systematic review

Assessment of Perigenital Sensitivity and Prostatic Mast Cell Activation in a Mouse Model of Neonatal Maternal Separation

“…Second, the behavioral and molecular changes resulting from NMS are largely due to dysregulation of the HPA axis [15][16][17][18] , suggesting that the effect is centrally-mediated and could have comorbid results, including changes in anxiety-and/or depression-like behaviors and increased sensitivity in other pelvic organs or more distant locations. This comorbid phenotype is indicative of what is commonly seen clinically and may be more representative of CP/CPPS patients as a whole 5,[28][29][30][31]42 . Third, based on these changes occurring as a result of HPA axis dysregulation, the impact of stress should be of utmost concern during both the NMS procedure and later behavioral testing and in vitro analysis.…”

“…We have previously demonstrated that the same NMS paradigm in female C57BL/6 mice produces vaginal hypersensitivity and abnormal gene expression in both the vagina and bladder suggestive of dysfunctional HPA axis output 16 . This evidence combined with the high prevalence of CP/CPPS patients presenting with other comorbidities 42 , including IC/PBS and mood disorders, that have more clearly been shown to be linked with early life stress exposure [12][13][14] , provides the rationale for using an NMS model to investigate CP/CPPS in mice.…”

New Independent Thermobalancing Treatment with Therapeutic Device for Chronic Prostatitis/Chronic Pelvic Pain Syndrome

“…Furthermore it was noticed that men with CP/CPPS responded in a more positive fashion to GTM provided by female physical therapists (13). Different psychosocial factors may play substantial role on men with CP/CPPS, such as stress, personality factors, social aspects as well as different psychiatric co-morbidities (depression, anxiety and trauma-related disorders, somatization disorder, substance abuse); and affect their quality of life -QoL (14).…”

Chronic inflammatory diseases of the rectum and prostate: a review of literature

“…Главными причинами являются отсутствие какого-либо конкрет-ного заболевания у отдельно обследованных пациентов или, наоборот, наличие нескольких различных болез-ней, включая психосоциальные, а также малая эффек-тивность проводимой терапии [6][7][8][9].…”

“…Не-обходимо проводить как можно больше исследований, чтобы понять взаимодействие психосоциальных фак-торов с ХП/СХТБ. Кроме того, эти факторы должны быть включены в подходы к лечению [8].…”