Abstract:Glutamate is our body’s primary excitatory neurotransmitter and plays a critical role in neuronal signaling allowing for the perception of the external world and the formation of memories. In excess, glutamate behaves as an excitotoxin that can induce neuronal apoptosis. Evidence exists that during head trauma neuronal cells can be exposed to supraphysiological concentrationsof glutamate causing damage or cell death. Both GABA receptor agonists and voltage-gated calcium channel blockers have been shown to have… Show more
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