Assessing Health-Related Quality of Life in Patients With Diabetic Foot Disease: Why Is It Important and How Can We Improve? The 2017 Roger E. Pecoraro Award Lecture

Wukich, Dane K.; Raspovic, Katherine M.

doi:10.2337/dci17-0029

Cited by 64 publications

(69 citation statements)

References 55 publications

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“…Due to its subjectivity, HRQoL is assessed as patient-reported outcome (PRO). It is considered an important outcome measure of medical treatment in addition to the clinical outcome measures [9]. Nowadays, HRQoL questionnaires are widely used and play a major role in healthcare decisions and treatment evaluation [10].…”

Section: Introductionmentioning

confidence: 99%

A translation and preliminary validation of the Dutch Wound-QoL questionnaire

et al. 2020

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Background: Chronic wounds have a major impact on patients' health-related quality of life (HRQoL). Therefore, measuring HRQoL is an indispensable part of the treatment of patients with chronic wounds. The aim of this study was to translate and validate the Wound-QoL, a wound-specific HRQoL questionnaire, in a Dutch population. Methods: The Wound-QoL was translated into Dutch according to the international standards. Patients with chronic wounds were asked to complete questionnaires at baseline (T0) and after six weeks (T1), including Wound-QoL, EQ-5D-3L (a generic questionnaire to measure HRQoL) and a visual analogue scale (VAS) measuring wound pain. If patients were not able to complete the questionnaire by themselves, it was read out to them by a nurse. Further data were obtained from medical records. Results: Of the 120 patients included, 64 (53.3%) completed the questionnaire by themselves. To 55 patients (45.8%), the questionnaire was read out. The internal consistency of the Wound-QoL global score was high at both time points (T0: Cronbach's α = 0.89, T1: Cronbach's α = 0.92). The item selectivity for global score ranged from r = 0.25 to r = 0.77 at T0 and from r = 0.40 to r = 0.79 at T1. Overall, the self-completion and read-out subgroups showed similar internal consistency and item selectivity scores. With regard to convergent validity, significant correlations were found between Wound-QoL and EQ-5D-3L (T0: r = − 0.45, p < 0.001, T1: r = − 0.50, p < 0.001) as well as between Wound-QoL and pain VAS (T0: r = 0.23, p = 0.012, T1: r = 0.37, p = 0.001) at both time points. Responsiveness analyses showed significant correlations between changes in Wound-QoL and changes in EQ-5D-3L (r = − 0.37, p < 0.001), pain VAS (r = 0.24, p = 0.044) and wound size (r = 0.24, p = 0.013). The self-completion and read-out subgroups showed differences in convergent validity and responsiveness. Conclusions: The results indicate that the Dutch version of the Wound-QoL has positive psychometric properties. However, more research is needed to further explore the differences between self-completed and read-out questionnaires.

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Section: Introductionmentioning

confidence: 99%

A translation and preliminary validation of the Dutch Wound-QoL questionnaire

et al. 2020

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“…Of all the variables included in the model, we observed that “low educational level” increases the risk of losing protective sensitivity (OR: 31.4, 95% CI: 2.5‐383.3, P = .007); however, the confidence interval is quite high, so the risk—although present—may be overestimated by the sample size. Those with a lower level of education typically have poorer health habits, causing increased obesity, physical inactivity, and susceptibility to psychosocial risks, which increases the risk of suffering from neuropathy . Therefore, it is important to establish preventative programs aimed at less educated populations to reduce the prevalence of PN.…”

Section: Discussionmentioning

confidence: 99%

Predictive model to identify the risk of losing protective sensibility of the foot in patients with diabetes mellitus

Chicharro‐Luna

Pomares

Ortega-Ávila

et al. 2019

International Wound Journal

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Diabetic neuropathy is defined as the presence of symptoms and signs of peripheral nerve dysfunction in diabetics. The aim of this study is to develop a predictive logistic model to identify the risk of losing protective sensitivity in the foot. This descriptive cross-sectional study included 111 patients diagnosed with diabetes mellitus. Participants completed a questionnaire designed to evaluate neuropathic symptoms, and multivariate analysis was subsequently performed to identify an optimal predictive model. The explanatory capacity was evaluated by calculating the R 2 coefficient of Nagelkerke. Predictive capacity was evaluated by calculating sensitivity, specificity, and estimation of the area under the receiver operational curve. Protective sensitivity loss was detected in 19.1% of participants. Variables associated by multivariate analysis were: educational level (OR: 31.4, 95% CI: 2.5-383.3, P = .007) and two items from the questionnaire: one related to bleeding and wet socks (OR: 28.3, 95% CI: 3.7-215.9, P = .001) and the other related to electrical sensations (OR: 52.9, 95% CI: 4.3-643.9, P = .002), which were both statistically significant. The predictive model included the variables of age, sex, duration of diabetes, and educational level, and it had a sensitivity of 81.3% and a specificity of 95.5%. This model has a high predictive capacity to identify patients at risk of developing sensory neuropathy.

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“…[17][18] Assessing the health-related quality of life (HRQOL) provides an opportunity to address specific physical or mental health concerns of patients. 16 Patients with diabetic foot ulcers often report low HRQOL.…”

Section: Discussionmentioning

confidence: 99%

A New Lease of Life - Living With Disability and Renal Dialysis

Yee¹,

Luke²,

Vasanwala³

2019

sfp

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Based on the National health Survey in 2010, almost half a million Singaporeans have diabetes, higher than the global prevalence. Diabetes is associated with a host of complications including heart disease, stroke, kidney failure, blindness and amputation. In 2016, Singapore declared a 'war on diabetes' to decrease the incidence of diabetes and its complications. Beyond providing healthcare resources, tackling diabetes requires the shifting of mindsets and changing of habits. The case study illustrates how biopsychosocial factors play a role in the optimal care of a diabetic patient. Self-management, acceptance, empowerment and health literacy are essential components to good diabetic care. System and support factors, as well as excellent communication with healthcare providers, are advocated as strategies to optimise outcome.

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Assessing Health-Related Quality of Life in Patients With Diabetic Foot Disease: Why Is It Important and How Can We Improve? The 2017 Roger E. Pecoraro Award Lecture

Cited by 64 publications

References 55 publications

A translation and preliminary validation of the Dutch Wound-QoL questionnaire

A translation and preliminary validation of the Dutch Wound-QoL questionnaire

Predictive model to identify the risk of losing protective sensibility of the foot in patients with diabetes mellitus

A New Lease of Life - Living With Disability and Renal Dialysis

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