2004
DOI: 10.1097/00003643-200402000-00009
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Assessing fluid responsiveness by stroke volume variation in mechanically ventilated patients with severe sepsis

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Cited by 104 publications
(50 citation statements)
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“…The American College of Critical Care Medicine guidelines for hemodynamic support of patients with sepsis also use CVP and PaOP to define resuscitation goals (6), yet the predefined increase in CI in the study by Osman et al (8) was seen after fluid bolus in only 46% of patients whose CVP was Ͻ12 mmHg and 54% of patients whose PaOP was Ͻ12 mmHg. These findings are congruous with the results of many other studies and strongly question the accuracy and utility of CVP and PaOP as predictors of preload and targets of volume therapy (3,5,13,18,19).…”
mentioning
confidence: 69%
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“…The American College of Critical Care Medicine guidelines for hemodynamic support of patients with sepsis also use CVP and PaOP to define resuscitation goals (6), yet the predefined increase in CI in the study by Osman et al (8) was seen after fluid bolus in only 46% of patients whose CVP was Ͻ12 mmHg and 54% of patients whose PaOP was Ͻ12 mmHg. These findings are congruous with the results of many other studies and strongly question the accuracy and utility of CVP and PaOP as predictors of preload and targets of volume therapy (3,5,13,18,19).…”
mentioning
confidence: 69%
“…The decrease in arterial pressure during expiration was the best predictor of improved cardiac function with volume (receiver operating characteristic 0.97) compared with PaOP (receiver operating characteristic 0.67). Marx et al (19) compared stroke volume variation (SVV) with PaOP and CVP as a predictor of volume responsiveness in patients with sepsis. SVV predicted the cardiovascular response to fluid, whereas the filling pressures were no better than chance in anticipating hemodynamic change (10).…”
mentioning
confidence: 99%
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“…The amount of change in LV stroke volume, called stroke volume variation, can shed light on the fluid status. Mechanical ventilation-induced haemodynamic changes in LV stroke volume can be very helpful in predicting the effect of volume expansion, termed fluid responsiveness [42][43][44][45][46]. The subject of fluid management is beyond the scope of this review.…”
Section: The Left Ventriclementioning
confidence: 99%
“…Even though data from the pulmonary artery catheter enables computation of a stroke volume estimate (CO/HR), more direct measurements of stroke volume are made possible by such innovations as the esophageal Doppler, non-invasive Doppler and pulse contour techniques. A growing body of literature supports the efficacy of SVO and SVV in sepsis (214,215). While the theoretical principle is clear, outcome studies using stroke volume and SVV for patients with sepsis are ongoing.…”
Section: B Improving Macrocirculationmentioning
confidence: 99%