Assessing chemical toxicity of ionic liquids on Vibrio fischeri : Correlation with structure and composition

Montalbán, Mercedes G.; Hidalgo, Juana M.; Collado-González, Mar; Baños, F. Guillermo Díaz; Víllora, Gloria

doi:10.1016/j.chemosphere.2016.04.042

Cited by 103 publications

(54 citation statements)

References 50 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…the ILs in this study were moderately toxic (decanoates and isostearates between 10–100 mg/L) or practically harmless (neodecanoates 100–1000 mg/L) according to their EC 50 values. Two EC 50 values, after 5 and 15 minutes incubation, are provided for reference purposes, since either of these incubation times is typically used in previous studies7131415161718192021222324252627282930313233343536373839 utilising V. fischeri bacteria. The toxic effect is time-dependent, particularly with relatively short incubation times (minutes time-scale).…”

Section: Resultsmentioning

confidence: 99%

Impact of Surface-Active Guanidinium-, Tetramethylguanidinium-, and Cholinium-Based Ionic Liquids on Vibrio Fischeri Cells and Dipalmitoylphosphatidylcholine Liposomes

Rantamäki

Ruokonen

Sklavounos

et al. 2017

Sci Rep

View full text Add to dashboard Cite

We investigated the toxicological effect of seven novel cholinium, guanidinium, and tetramethylguanidinium carboxylate ionic liquids (ILs) from an ecotoxicological point of view. The emphasis was on the potential structure-toxicity dependency of these surface-active ILs in aqueous environment. The median effective concentrations (EC50) were defined for each IL using Vibrio (Aliivibrio) fischeri marine bacteria. Dipalmitoylphosphatidylcholine (DPPC) liposomes were used as biomimetic lipid membranes to study the interactions between the surface-active ILs and the liposomes. The interactions were investigated by following the change in the DPPC phase transition behaviour using differential scanning calorimetry (DSC). Critical micelle concentrations for the ILs were determined to clarify the analysis of the toxicity and the interaction results. Increasing anion alkyl chain length increased the toxicity, whereas branching of the chain decreased the toxicity of the ILs. The toxicity of the ILs in this study was mainly determined by the surface-active anions, while cations induced a minor impact on the toxicity. In the DSC experiments the same trend was observed for all the studied anions, whereas the cations seemed to induce more variable impact on the phase transition behaviour. Toxicity measurements combined with liposome interaction studies can provide a valuable tool for assessing the mechanism of toxicity.

show abstract

Section: Resultsmentioning

confidence: 99%

Impact of Surface-Active Guanidinium-, Tetramethylguanidinium-, and Cholinium-Based Ionic Liquids on Vibrio Fischeri Cells and Dipalmitoylphosphatidylcholine Liposomes

Rantamäki

Ruokonen

Sklavounos

et al. 2017

Sci Rep

View full text Add to dashboard Cite

show abstract

“…Toxicological assays initially mainly focused on the aquatic impact of ILs; however, over time, data on the phytotoxicity, cytotoxicity, genotoxicity, antimicrobial activity, and enzymatic inhibition have also been reported. Moreover, a series of in silico models have been developed to predict the toxicity of ILs to different living organisms, such as Daphnia magna , Vibrio fischeri , acetylcholinesterase enzyme, and cell lines . Recent data demonstrate that not only internal factors, such as the chemical structure of the ILs, but also external factors can influence the toxicity of ILs, including the selected biological system and the experimental conditions.…”

Section: Toxicological Impact Of Ionic Liquidsmentioning

confidence: 99%

“…The obtained data are in agreement with the results based on in vivo toxicological assays in terms of the less‐important contribution of the anions to the toxicity of the ILs. The “side‐chain effect” is the main factor influencing the toxicity on the V. fischeri bacterium, and the presence of functional groups in the side chain also has an effect by decreasing the toxicity . Similarly, the anion shows a lower contribution to the toxicity of the ILs, and ILs with a fluorine anion exhibit the lowest EC 50 values .…”

Section: Toxicological Impact Of Ionic Liquidsmentioning

confidence: 99%

“…The “side‐chain effect” is the main factor influencing the toxicity on the V. fischeri bacterium, and the presence of functional groups in the side chain also has an effect by decreasing the toxicity . Similarly, the anion shows a lower contribution to the toxicity of the ILs, and ILs with a fluorine anion exhibit the lowest EC 50 values . A mathematical model using extended topochemical atom (ETA) indices to assess the chemical features of the ILs responsible for their ecotoxicity towards the green algae S. vacuolatus has been implemented by Narayan and Roy .…”

Section: Toxicological Impact Of Ionic Liquidsmentioning

confidence: 99%

See 1 more Smart Citation

Environmental Impact of Ionic Liquids: Recent Advances in (Eco)toxicology and (Bio)degradability

et al. 2017

View full text Add to dashboard Cite

This Review aims to integrate the most recent and pertinent data available on the (bio)degradability and toxicity of ionic liquids for global and critical analysis and on the conscious use of these compounds on a large scale thereafter. The integrated data will enable focus on the recognition of toxicophores and on the way the community has been dealing with them, with the aim to obtain greener and safer ionic liquids. Also, an update of the most recent biotic and abiotic methods developed to overcome some of these challenging issues will be presented. The review structure aims to present a potential sequence of events that can occur upon discharging ionic liquids into the environment and the potential long-term consequences.

show abstract

“…Ionic Liquids. The toxicity of twenty-nine imidazolium-, pyridinium-and ammonium-based ionic liquids towards the bioluminescent photobacterium Vibrio fischeri has been reported by Montalbán et al, (2016 . Among the 20 test RAPD primers, 13 primers with 60-70% GC content produced unique polymorphic band profiles.…”

Section: Polychlorinated Biphenyls (Pcbsmentioning

confidence: 99%

Effects of Pollution on Freshwater Organisms

Choudri

Baawain²

2017

Water Environment Research

View full text Add to dashboard Cite

This review covers research papers and scientific literature published in the year 2016 on the effects of anthropogenic pollutants on freshwater organisms. In the first, the review begins with two broad sections thate are mainly focused on research reviews and broad field studies and surveys. This is followed by reviews of research categorized in sections to reflect the pollutant class. These sections include wastewater, stormwater and non-point source pollution, nutrients, sediment cap materials and suspended clays, botanical extracts, surfactants, metals, persistent organic pollutants, pharmaceuticals, endocrine disruptors, pesticides, petroleum hydrocarbons and polycyclic aromatic hydrocarbons (PAHs), ionic liquids, and nanomaterials. The final section of the review highlights the research published on describing innovations in the field of freshwater pollution research.

show abstract

Assessing chemical toxicity of ionic liquids on Vibrio fischeri : Correlation with structure and composition

Cited by 103 publications

References 50 publications

Impact of Surface-Active Guanidinium-, Tetramethylguanidinium-, and Cholinium-Based Ionic Liquids on Vibrio Fischeri Cells and Dipalmitoylphosphatidylcholine Liposomes

Impact of Surface-Active Guanidinium-, Tetramethylguanidinium-, and Cholinium-Based Ionic Liquids on Vibrio Fischeri Cells and Dipalmitoylphosphatidylcholine Liposomes

Environmental Impact of Ionic Liquids: Recent Advances in (Eco)toxicology and (Bio)degradability

Effects of Pollution on Freshwater Organisms

Contact Info

Product

Resources

About