Assessing changes to N95 respirator filtration efficiency, qualitative and quantitative fit, and seal check with repeated vaporized hydrogen peroxide (VHP) decontamination

Yen, Christina F; Seeley, R.; Gordon, Peter E.; Parameswaran, Lalitha; Wright, Sharon B.; Pepe, Dana; Mehrotra, Preeti

doi:10.1016/j.ajic.2021.11.005

Cited by 4 publications

(3 citation statements)

References 3 publications

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“… 19 Although the availability of N95s has increased significantly over the course of the pandemic, prices have also increased and uncertainty remains in how the COVID-19 pandemic will continue to evolve. Nevertheless, studies have increasingly suggested that N95s can be decontaminated and reused 20 , 21 ; taken together with our findings implies that healthcare systems could prioritize reuse, particularly for OR procedures.…”

Section: Discussionsupporting

confidence: 59%

Brief Cost Analysis of Surgical Personal Protective Equipment During the COVID-19 Pandemic

2022

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Section: Discussionsupporting

confidence: 59%

Brief Cost Analysis of Surgical Personal Protective Equipment During the COVID-19 Pandemic

2022

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“…Therefore, it was concluded that it is safe to use once-autoclave-resterilized surplus un-coated polyester grafts, provided sterility is guaranteed. Moreover, Yen et al (2022) also showed that 25 cycles of vaporized hydrogen peroxide reprocessing of 3M 1860/1860S N95 respirators did not compromise filtration efficiency, seal check, or qualitative and quantitative fit.…”

mentioning

confidence: 89%

Validation of a method to elute viruses from different types of face masks

El‐Senousy¹,

Abdellatif

Ahmed

et al. 2022

J Exp Bio & Ag Sci

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Due to the SARS-CoV-2 pandemic, it is crucial to study the efficiency of face masks in retaining viruses for the upcoming years. The first objective of this study was to validate a method to elute viruses from polyester and cotton face masks. We observed that deionized water followed by 3% beef glycine (pH 9.5 or pH 7.2) was significantly more efficient (p < 0.05) in eluting the bacteriophage phiX174 virus from polyester (4.73% ± 0.25% to 28.67% ± 1.89%), polyester/cotton (3% ± 0.33%), and cotton (1.7% ± 0.21%) face masks than 3% beef glycine only (pH 9.5 or pH 7.2) as a single eluent (3.4% ± 0.16% to 21.33% ± 0.94% for polyester, 1.91% ± 0.08% for polyester/cotton, and 1.47% ± 0.12% for cotton face masks). Also, deionized water was significantly less efficient as a single eluent for eluting bacteriophage phiX174 from all the studied face mask types. The polyethylene glycol (PEG) precipitation method was substantially more efficient (p < 0.05) as a second step concentration method for the viruses in the eluates than the organic flocculation (OF) method. Higher viral loads were eluted from polyester face masks than cotton ones. We also found varying viral loads in the eluate solutions from different commercial polyester face masks, with the highest percentage seen for the N95 face mask. The second objective was to apply the validated method to study the effect of autoclaving on the different face mask materials. Results of the study did not show any significant differences in the viral loads eluted from the studied face masks before and after one and five autoclaving cycles. Moreover, a scanning electron microscope (SEM) analysis revealed no changes in the yarns, elongation, tensile strength, and contact angle measurements of the polyester or cotton materials after one or five autoclaving cycles.

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“…As the COVID-19 pandemic forced us to consider novel methodologies for reuse, it also proliferated the use of under-used PPE such as reusable respirators. Thinking practically and creatively will be critical to maintaining PPE supply chain resilience [21,22].…”

Section: Personal Protective Equipmentmentioning

confidence: 99%

Resource sustainability and challenges in the supply chain: implications for infection prevention

Mehrotra,

Desai

2024

Current Opinion in Infectious Diseases

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Purpose of review Infection prevention and control practices remain the bedrock of healthcare associated infection prevention and outbreak and epidemic control efforts. However, issues in supply chain management can hinder these efforts, as exemplified by various public health emergencies. This review explores the key role of supply chains in infection prevention and explores specific challenges. Recent findings In all of the critical components of infection prevention and control – hand hygiene, personal protective equipment, sterile supplies, environmental disinfection, and waste management – disruptions in supply chains have led to limited availability and dissemination. Summary Strategies to mitigate these resource constraints in the inter-epidemic period will also be highlighted. The infection prevention workforce is well poised to inform supply chain dynamics. Without robust and adequate supply chains, infection prevention and control efforts suffer which perpetuates healthcare-associated infections, clusters, and epidemics.

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Assessing changes to N95 respirator filtration efficiency, qualitative and quantitative fit, and seal check with repeated vaporized hydrogen peroxide (VHP) decontamination

Cited by 4 publications

References 3 publications

Brief Cost Analysis of Surgical Personal Protective Equipment During the COVID-19 Pandemic

Brief Cost Analysis of Surgical Personal Protective Equipment During the COVID-19 Pandemic

Validation of a method to elute viruses from different types of face masks

Resource sustainability and challenges in the supply chain: implications for infection prevention

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