Assessing Atrazine-Induced Toxicities in Bufo bufo gargarizans Cantor

Sai, Linlin; Wu, Qianhong; Qu, Binpeng; Bo, Cunxiang; Yu, Gongchang; Jia, Qiang; Xie, Liangdi; Li, Yuezhong; Guo, Qiming; Ng, J. C.; Peng, Cheng

doi:10.1007/s00128-014-1441-0

Cited by 10 publications

(9 citation statements)

References 21 publications

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“…(Sai et al 2016); the score for relevance was 1.75 (see SI). A similar study (85-day exposure) of tadpoles of the frog Bufo bufo gargarizan resulted in mortality ranging from 20% at 0.1 mg/L to 30% at 100 mg/L (Sai et al 2015). This response received a score of 3 for relevance (see SI); however, the results are inconsistent with other observations in X. laevis ( Figure 6) and are unexpected for B. b. gargarizan.…”

Section: Survival Of Fish and Amphibians After Long-term Exposures Tomentioning

confidence: 81%

“…As responses were observed at >100 lg/L, the score for relevance was reduced to 0. In larvae of X. laevis and B. b. gargarizan exposed to 0.1, 1, 10, 100 mg atrazine/L for 90 d (Sai et al 2016) and 85 d (Sai et al 2015), respectively, no effects on length and/or weight were reported.…”

Section: Weight And/or Size Of Fish Amphibiansmentioning

confidence: 94%

“…In the course of the analysis, two papers overlooked during the development of the original WoE assessment were identified and analyzed. In the end, the papers included in the QWoE update are: (Chang et al 2005;Hecker et al 2005;Svartz et al 2012;Ghodageri and Katti 2013;Olker 2014;Shenoy 2014;Baxter et al 2015;Chen et al 2015;Sai et al 2015Sai et al , 2018Syngenta 2015Syngenta , 2017aSyngenta , 2017bVan Der Kraak et al 2015;Wirbisky and Freeman 2015;dos Santos Mendonc¸a et al 2016;Ehrsam et al 2016;Gustafson et al 2016;Khan et al 2016aKhan et al , 2016bKhan et al , 2016cLiu et al 2016;Richter et al 2016;Russart and Rhen 2016;Tulaby Dezfuly and Mohammadian 2016;Wirbisky et al 2016aWirbisky et al , 2016bWirbisky et al , 2016cD'Angelo and Freeman 2017;Du Gas et al 2017;Hoskins et al 2017;Jones et al 2017;Khalil et al 2017;Kirsten et al 2017;McMahon et al 2017;Persch et al 2017;Scott et al 2017;Shukla et al 2017;Snyder et al 2017;Wang et al 2017;…”

Section: Methodsmentioning

confidence: 99%

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Effects of atrazine on fish, amphibians, and reptiles: update of the analysis based on quantitative weight of evidence

Hanson

Solomon

Kraak

et al. 2019

Critical Reviews in Toxicology

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Quantitative weight of evidence (QWoE) provides a framework and process for evaluating different toxicological studies based on quality and relevance of the results. This framework allows for data from these studies to be combined in separate lines of evidence to address causality, and relevance to environmental risks. In 2014, such a QWoE that examined the body of available company reports and peer reviewed literature regarding the effects of the herbicide atrazine on fish, amphibians, and reptiles was published. Since that time, new studies have been conducted and/or published. One of the advantages of the QWoE framework is that additional information can be added as it becomes available. Thus, these new studies were evaluated in the same manner as previously and the new data incorporated into the existing QWoE. As before, the new updated QWoE was based on the same process of objective scoring of individual studies with respect to the quality of the methods and the relevance of individual responses to the apical endpoints of survival, growth, development, and reproduction. These new data did not identify new responses or indicate any relevant effects of atrazine. The new updated QWoE analysis concluded that atrazine does not adversely affect fish, amphibians, and reptiles, at environmentally relevant concentrations (<100 mg atrazine/L), which is consistent with the previous conclusions. These new studies and data are discussed in this paper and the accompanying supplement information provides detailed and transparent information to support these conclusions.

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Section: Survival Of Fish and Amphibians After Long-term Exposures Tomentioning

confidence: 81%

Section: Weight And/or Size Of Fish Amphibiansmentioning

confidence: 94%

Section: Methodsmentioning

confidence: 99%

See 1 more Smart Citation

Effects of atrazine on fish, amphibians, and reptiles: update of the analysis based on quantitative weight of evidence

Hanson

Solomon

Kraak

et al. 2019

Critical Reviews in Toxicology

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show abstract

“…Similarly, ATZ did not affect the survival of larval Acris blanchardi and Osteopilus septentrionalis (Ehrsam et al, 2016; Hoskins & Boone, 2018) but caused retarded growth in larval Anaxyrus americanus , Rhinella arenarum, Lithobates clamitans, Ambystoma maculatum , and Ambystoma texanum (Rohr & McCoy, 2010). In contrast, treatment of larval Bufo bufo gargarizan (Sai et al, 2015), R. arenarum (Svartz et al, 2012), Silurana tropicalis (Saka et al, 2018), Xenopus laevis (Chen et al, 2015; Rimayi et al, 2018) to ATZ resulted in mortality and increased growth rate in larval Hyla chrysoscelis, Ambystoma barbouri, Ambystoma macrodactylum , and A. tigrinum (Rohr & McCoy, 2010). Retarded growth of anuran tadpoles caused by ATZ could be due to changes in the secretion of CRH in the hypothalamus, which in turn, increases the secretion of ACTH and ultimately glucocorticoids (corticosterone in amphibians).…”

Section: Discussionmentioning

confidence: 99%

Does atrazine induce changes in predator recognition, growth, morphology, and metamorphic traits of larval skipper frogs (Euphlyctis cyanophlyctis)?

Supekar¹,

Gramapurohit

2022

J Exp Zool Pt A

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Atrazine, an info disruptor, interferes with the olfaction of aquatic organisms by impairing the chemosensory system. Consequently, it affects behavior, physiology, and growth increases mortality and infections, and suppresses the immune system of aquatic animals. In this study, we wanted to determine the sensitivity of larval Euphlyctis cyanophlyctis to different concentrations of atrazine by assessing their antipredator behavior, growth, morphology, and metamorphic traits. The results indicate that exposure to atrazine did not affect the survival of tadpoles. However, it caused retarded growth at higher concentrations. Interestingly, the antipredator behavior of tadpoles toward conspecific alarm cues decreased in a dose‐dependent manner with an increase in the concentration of atrazine. Tadpoles exposed to low concentrations of atrazine had deeper, wider bodies and tails while those exposed to higher concentrations had shallower and narrower bodies with shallower tail muscles. However, at low and moderate concentrations atrazine did not affect size at metamorphosis, it extended the larval duration at higher concentrations.

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“…Atrazine concentrations measured in some samples, however, were similar to or exceeded those reported by some studies as causing adverse effects to aquatic biota, including amphibians and fish, although the exceedances in the present study typically were for shorter periods than those investigated in chronic exposures. For example, Sai et al (2015) reported that atrazine concentrations of 10 µg/L over 85-day exposures inhibition of metamorphosis and hindlimb extension and changes in testicular structure of the toad Bufo bufo gargarizans Cantor. This concentration was exceeded in about 1% of weekly and 2-day samples, but was exceeded at no site in more than three successive weekly samples, thus for less than 85 days.…”

Section: Implications For Aquatic Biota and Drinking Watermentioning

confidence: 99%

Similarities and differences in occurrence and temporal fluctuations in glyphosate and atrazine in small Midwestern streams (USA) during the 2013 growing season

Mahler

Metre

Burley

et al. 2017

Science of The Total Environment

104

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Glyphosate and atrazine are the most intensively used herbicides in the United States. Although there is abundant spatial and temporal information on atrazine occurrence at regional scales, there are far fewer data for glyphosate, and studies that compare the two herbicides are rare. We investigated temporal patterns in glyphosate and atrazine concentrations measured weekly during the 2013 growing season in 100 small streams in the Midwestern United States. Glyphosate was detected in 44% of samples (method reporting level 0.2μg/L); atrazine was detected above a threshold of 0.2μg/L in 54% of samples. Glyphosate was detected more frequently in 12 urban streams than in 88 agricultural streams, and at concentrations similar to those in streams with high agricultural land use (>40% row crop) in the watershed. In contrast, atrazine was detected more frequently and at higher concentrations in agricultural streams than in urban streams. The maximum concentration of glyphosate measured at most urban sites exceeded the maximum atrazine concentration, whereas at agricultural sites the reverse was true. Measurement at a 2-day interval at 8 sites in northern Missouri revealed that transport of both herbicide compounds appeared to be controlled by spring flush, that peak concentration duration was brief, but that peaks in atrazine concentrations were of longer duration than those of glyphosate. The 2-day sampling also indicated that weekly sampling is unlikely to capture peak concentrations of glyphosate and atrazine.

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Assessing Atrazine-Induced Toxicities in Bufo bufo gargarizans Cantor

Cited by 10 publications

References 21 publications

Effects of atrazine on fish, amphibians, and reptiles: update of the analysis based on quantitative weight of evidence

Effects of atrazine on fish, amphibians, and reptiles: update of the analysis based on quantitative weight of evidence

Does atrazine induce changes in predator recognition, growth, morphology, and metamorphic traits of larval skipper frogs (Euphlyctis cyanophlyctis)?

Similarities and differences in occurrence and temporal fluctuations in glyphosate and atrazine in small Midwestern streams (USA) during the 2013 growing season

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