Assesment of Psychiatric Symptoms and Co-morbidities in Patients with Irritable Bowel Syndrome

Sertbaş, Yaşar; Belli, Hasan; Pişkinpaşa, Nezih; Ural, Cenk; Akbudak, Mahir; Sertbaş, Meltem; Öncü, Fatih

doi:10.7727/wimj.2012.166

Cited by 10 publications

(9 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The rapid degradation of tryptophan depletes tryptophan and serotonin and produces toxic metabolites. This mechanisms could represent a possible biological basis for the high co-morbidity between IBS and depressive and anxiety disorders [63, 64]. …”

Section: Reviewmentioning

confidence: 99%

The relationship between irritable bowel syndrome and psychiatric disorders: from molecular changes to clinical manifestations

et al. 2014

View full text Add to dashboard Cite

Irritable bowel syndrome (IBS) is a functional syndrome characterized by chronic abdominal pain accompanied by altered bowel habits. Although generally considered a functional disorder, there is now substantial evidence that IBS is associated with a poor quality of life and significant negative impact on work and social domains. Neuroimaging studies documented changes in the prefrontal cortex, ventro-lateral and posterior parietal cortex and thalami, and implicate alteration of brain circuits involved in attention, emotion and pain modulation. Emerging data reveals the interaction between psychiatric disorders including generalized anxiety disorder, panic disorder, major depressive disorder, bipolar disorder, and schizophrenia and IBS, which suggests that this association should not be ignored when developing strategies for screening and treatment. Psychological, social and genetic factors appear to be important in the development of IBS symptomatology through several mechanisms: alteration of HPA axis modulation, enhanced perception of visceral stimuli or psychological vulnerability. Elucidating the molecular mechanisms of IBS with or without psychiatric comorbidities is crucial for elucidating the pathophysiology and for the identification of new therapeutical targets in IBS.

show abstract

Section: Reviewmentioning

confidence: 99%

The relationship between irritable bowel syndrome and psychiatric disorders: from molecular changes to clinical manifestations

et al. 2014

View full text Add to dashboard Cite

show abstract

“…According to Gomez [2] approximately 30% -65% of medically-ill patients suffer from a co-morbid mental health problem that adversely affects quality of care, adherence to treatment and cost of services [3]. Studies suggest that up to 34% of patients suffering from irritable bowel syndrome also have at least one comorbid psychiatric diagnosis [4]. Patients diagnosed with HIV have co-morbid psychiatric diagnosis in more than 48% of admitted cases [5].…”

Section: Introductionmentioning

confidence: 99%

Estimation of Costs-Savings and Improved Patient Outcomes of Implementing a Consultation-Liaison Service at Health Sciences North

Okoronkwo¹

2019

OJPsych

View full text Add to dashboard Cite

Objective: The study was conducted to assess the implementation of a psychiatric consultation-liaison service (C-L) from the perspective of cost-savings, staff satisfaction, patient satisfaction and to assess the general features of patients referred to the C-L service. Methodology: Cost-savings were evaluated using a large cohort of referrals to the hospital were identified using data derived from the Institute of Clinical Evaluative Sciences (N = 2246); these data were divided into pre and post periods with respect to imitation of the C-L service. To evaluate staff satisfaction, 170 nurses and physicians completed an online survey. Patient satisfaction was assessed through a survey assessing various aspects of their experiences with the C-L service that was completed by each patient (N = 40). Finally referrals to the C-L service (N = 445) were analyzed to discern indicators of the C-L service's efficacy (i.e. reasons for referral, time to accommodate referral). Results: The data indicated: 1) a reduction in the number of re-admissions and length of stay after the initiation of the C-L service translating into significant cost-savings for the hospital, 2) that increased staff satisfaction was associated with providing confidence, support, and improved communication, and 3) that the C-L service accommodated approximately 90% of patients within 1 day. Conclusion: The results of this study support stakeholders' decisions to implement C-L services and also indicate areas of improvement that may improve the quality of C-L services within other institutions.

show abstract

“…[10] The disorders that were encountered frequently included depression, anxiety, somatization disorder, and substance use disorder, which is in agreement with the previous literature. [9101213] The present study finds that the rates of psychiatric diagnosis were higher than patients with NUD, even after controlling for other variables. Two previous studies, however, did not find differences in psychiatric morbidity between patients with IBS and peptic ulcer disease.…”

Section: Discussionmentioning

confidence: 41%

“…[89] It has been seen that up to 90% of patients with IBS may have associated psychiatric disorders. [1011] The disorders commonly encountered in patients with IBS include depression,[910] generalized anxiety,[910] panic disorder,[910] somatization disorder,[912] and substance use disorders. [13] Anxiety and depression have been noticed to be important concomitants of IBS and adversely affect patient outcomes.…”

mentioning

confidence: 99%

Comparison of psychiatric morbidity in patients with irritable bowel syndrome and non-ulcer dyspepsia

et al. 2016

View full text Add to dashboard Cite

Background and Aims:The present study aimed to find psychiatric morbidity, stress, anxiety, and depression in patients with irritable bowel syndrome (IBS) and compare it with patients having non-ulcer dyspepsia (NUD).Methods:This case NUD study compared 50 patients each with IBS and NUD. The two groups were compared on demographic data, psychiatric diagnosis using the Structured Clinical Interview for DSM-IV Axis 1 disorders, anxiety levels using the Hamilton Anxiety Rating Scale (HAM-A), and depression using the Hamilton Depression Rating Scale (HAM-D). The Presumptive Stressful Life Events Scale (PSLES) was used to measure stress.Results:The cases of IBS were more likely to be of female gender (P = 0.012), married (P = 0.009), and employed (P < 0.001). Psychiatric diagnoses were more common in the cases of IBS than NUDs (88% vs. 30%, P < 0.001), the most common being major depression and somatization disorder. Symptoms of anxiety and depression were more common in patients with IBS (P < 0.001 for HAM-A and HAM-D). Logistic regression revealed that having IBS and increased age were independent predictors of having a psychiatric diagnosis.Conclusions:IBS is associated with the considerable degree of psychiatric morbidity. Adequate attention should be paid toward comorbid psychiatric illnesses, and prompt treatment should be instituted.

show abstract

Assesment of Psychiatric Symptoms and Co-morbidities in Patients with Irritable Bowel Syndrome

Cited by 10 publications

References 16 publications

The relationship between irritable bowel syndrome and psychiatric disorders: from molecular changes to clinical manifestations

The relationship between irritable bowel syndrome and psychiatric disorders: from molecular changes to clinical manifestations

Estimation of Costs-Savings and Improved Patient Outcomes of Implementing a Consultation-Liaison Service at Health Sciences North

Comparison of psychiatric morbidity in patients with irritable bowel syndrome and non-ulcer dyspepsia

Contact Info

Product

Resources

About