Assesment of Insulin Resistence in Different Stages of Chronic Kidney Disease

Abstract

Introduction: Epidural anaesthesia and analgesia has justified use in the perioperative care of high-risk surgical patients, as they give better analgesia, and also improved outcome. Thoracic Epidural analgesia is an excellent method of postoperative and post injury pain control in procedures involving significant thoracic and abdominal injury weather traumatically or surgically induced. Though Bupivacaine is considered to be the drug of choice, many other agents are being used for epidural anesthesia. Material and Methods: This study was carried out on 105 ASA grade I and II nulliparous patients, between 20 to 70 years of age undergoing laparotomy, voluntary donor nephrectomy and renal surgeries. They were randomly divided in the Buprenorphine, Bupivacaine and Fentanyl Groups. Quality of analgesia and post-operative complications were monitored. Results: Analgesic failure was observed in all the three Groups. But complete pain relief was better in the Buprenorphine Group. Also, complications (hypotension, bradycardia, sedation) were less in the Buprenorphine Group than in the Bupivacaine and Fentanyl Groups. Conclusion: Buprenorphine is safer and provides better quality analgesia than Bupivacaine and Fentanyl.