Assembly of kafirin/carboxymethyl chitosan nanoparticles to enhance the cellular uptake of curcumin

Encapsulation and protection of resveratrol in kafirin and milk protein nanoparticles

“…The turbidity of kafirin solution was about 88% (Fig. a), due to that the protein is hydrophobic in nature and susceptible to coagulation (Xiao et al ., ). Mean diameter of kafirin particles was 189 nm (Fig.…”

“…In the fabrication of prolamin nanoparticles, an aqueous solution of hydrophilic biopolymers is generally used as anti‐solvent phase (Davidov‐Pardo et al ., ; Xiao et al ., ). Carboxymethyl‐chitosan improved encapsulation efficiency and photo‐stability of curcumin in kafirin particles (Xiao et al ., ).…”

Oral delivery strategies for nutraceuticals: Delivery vehicles and absorption enhancers

“…Curcumin was complexed into chitosan-zein particulates, improved thermal and UV stability 431 and anti-oxidative scavenging capacity was retained . Similarly, when 432 curcumin was complexed in a carboxymethyl chitosan-kafirin (a prolamin protein from 433 sorghum) particulates, it again improved UV stability and improved cellular uptake in Caco-2 434 (Xiao, Nian, & Huang, 2015). EGCG is an abundant polyphenol from green tea and a potent 435 antioxidant; it had a burst release profile and retained cytotoxicity against cancer cell lines in 436 vitro when complexed in a chitosan-caseinophosphopeptide particulate (Hu, Xie, Zhang, & 437 Zeng, 2014).…”

Novel nanoparticle materials for drug/food delivery-polysaccharides

“…Antioxidants, probiotics, polyunsaturated fatty acids, and proteins are common bioactives that can be added to food to improve nutritional value, to prevent diseases and to improve overall health [212]. Nanodelivery of these components may improve their stability [213,214], solubility [215,216], functionality [217,218], cellular uptake [219][220][221], and bioavailability [222][223][224] and may also provide controlled release [225][226][227] for better efficacy of the bioactive.…”