“…4,5 Porous materials are promising carriers for enzyme immobilization as they could offer channels for mass transfer, 6,7 and conformational confinement to stabilize enzymes. 8,9 Especially, covalent organic frameworks (COFs) as a class of crystalline porous materials, 10,11 have attractive properties, including ultrahigh porosity, predesignable structure, and high stability, 12 which make them ideal hosts for enzyme immobilization. Nevertheless, the preparation of COFs-based enzyme immobilization systems with high activity and stability is still a serious challenge, due to the intrinsic drawbacks of existing immobilization methods.…”