Assafoetidin and ferocolicin, two sesquiterpenoid coumarins from ferula assafoetida regel

Newα-Glucosidase Inhibitors from the Mongolian Medicinal PlantFerula mongolica

“…The HMBC spectrum established correlations of HÀC(5') (d 7.50) of ring A with C(9') (d 158.2) and C(4') (167.2) and also of HÀC(8') (d 6.73) of ring A with C(10') (d 106.2) and C(4') (d 167.2), further confirming the presence of a coumarin moiety[10] [12][13]. The absence of typical pairs of d for HÀC(3') and HÀC(4') indicated that C(3') and C(4') were substituted in 3[14]. Comparison of its 1 H-and 13 C-NMR data with those reported for similar structures allowed to determine the fusion site of the furan ring C [5][9].…”

Essential Oil Composition ofFerula assa-foetidaL. from Iran

“…There are other references about sesquiterpenoid coumarins in F. mu-foetidu (18)(19)(20). Also, volatile polysulfides were found in asafoetida (21).…”

A New Ester Isolated fromFerula assa-foetidaL.

“…Asadisulphide, 14) disulfides, as well as symmetric triand tetrasulfides have been isolated, 15) and polysulfide derivatives have recently been reported, as well as umbelliferone, farnesiferol A, B and C, and ferulic acid, 16,17) kamolonol, 18) assafoetidin and ferocolicin, 19) assacoumarin A and B, 14) foetidin, 20) episamarcandin, umbelliprenin and conferol, 21) 5-hydroxyumbelliprenin, 8-hydroxyumbelliprenin and 8-acetoxyumbelliprenin, 22) and episamarcandin acetate. 23) As part of our continuing studies of plants of the Ferula genus, [24][25][26][27][28] this present work deals with the isolation of a new caffeic acid cinnamyl ester from the gum resin of Ferula assafoetida and its activity in inhibiting NO production.…”