2018
DOI: 10.1002/uog.19019
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ASPRE trial: incidence of preterm pre‐eclampsia in patients fulfilling ACOG and NICE criteria according to risk by FMF algorithm

Abstract: In women who are screen positive for preterm PE by the ACOG or NICE criteria but screen negative by the FMF algorithm, the risk of preterm PE is reduced to within or below background levels. The results provide further evidence to support the personalized risk-based screening method that combines maternal factors and biomarkers. Copyright © 2018 ISUOG. Published by John Wiley & Sons Ltd.

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Cited by 62 publications
(55 citation statements)
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References 18 publications
(28 reference statements)
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“…After combined screening, in some of these women the risk is increased substantially, whereas in others the risk is reduced substantially to below the background risk of the whole population. Similarly, we have reported previously that, in ACOG or NICE screen‐positive women who are screen positive by the FMF algorithm, the incidence of preterm PE is increased substantially, whereas, in the FMF screen‐negative group, the incidence is reduced to within or below background levels.…”
Section: Discussionsupporting
confidence: 77%
“…After combined screening, in some of these women the risk is increased substantially, whereas in others the risk is reduced substantially to below the background risk of the whole population. Similarly, we have reported previously that, in ACOG or NICE screen‐positive women who are screen positive by the FMF algorithm, the incidence of preterm PE is increased substantially, whereas, in the FMF screen‐negative group, the incidence is reduced to within or below background levels.…”
Section: Discussionsupporting
confidence: 77%
“…In 2360 (6.8%) pregnancies with at least two of the NICE moderate‐risk criteria, the incidence of preterm PE was 1.74% (95% CI, 1.28–2.35). In the subgroups of screen positive and screen negative by the Bayes method the incidence was 4.91% (95% CI, 3.54–6.79) and 0.42% (95% CI, 0.20–0.86), respectively, and the relative incidence was 0.085 (95% CI, 0.038–0.192) . These results provide further evidence to support risk‐based screening using biomarkers.…”
Section: First Trimester Prediction Of Pre‐eclampsiamentioning
confidence: 60%
“…6.1). According to the recommendation of the Foetal Medicine Foundation (FMF), BP should be measured simultaneously in both arms [102,103].…”
Section: Risk Assessment Prevention and Diagnosismentioning
confidence: 99%