Aspirin as a promising drug for slow coronary flow

Jiang, Mengdi; Wu, Ming-yue; Wu, Mengyin; Liang, Meng

doi:10.1016/j.mehy.2012.07.022

Cited by 1 publication

(1 citation statement)

References 19 publications

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“…Aspirin can be used in treatment of SCF [33]. It has been demonstrated that mean platelet volume significantly increased in patients with SCF, altered platelet reactivity and aggregation which may require effective anti-platelet therapy [34].…”

Section: Discussionmentioning

confidence: 99%

Plasma lipoprotein (a) levels in patients with slow coronary flow

Yücel

Doğan²,

Altınbaş³

et al. 2013

pwki

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IntroductionSlow coronary flow (SCF) is a microvascular disorder characterized by delayed opacification of coronary vessels with normal coronary angiogram. It may be due to endothelial dysfunction and diffuse atherosclerosis. Lipoprotein(a) [Lp(a)] is related to cardiovascular events. Plasma Lp(a) levels have not been studied previously in SCF patients.AimWe investigated plasma Lp(a) and fibrinogen levels, and their relation to coronary flow rate in patients with SCF.Material and methodsThis cross-sectional study included 50 patients with SCF and 30 age- and sex-matched controls who had normal coronary arteries and normal flow. Coronary flow rates of patients and controls were counted with the thrombolysis in myocardial infarction (TIMI) frame count. Plasma Lp(a) and fibrinogen levels were measured in SCF patients and controls, with routine biochemical tests.ResultsThere were no significant differences between the two groups with respect to plasma Lp(a) (21 mg/dl vs. 14 mg/dl, p = 0.11) and fibrinogen (278 mg/dl vs. 291 mg/dl, p = 0.48) levels. The TIMI frame count was not correlated with plasma Lp(a) (r = 0.13, p = 0.25) or fibrinogen (r = –0.14, p = 0.28) levels.ConclusionsOur results show that there is no significant association between SCF and Lp(a) and fibrinogen levels.

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Section: Discussionmentioning

confidence: 99%