Aspiration Lung Disease

Benedictis, Fernando Maria de; Carnielli, Virgilio P.; Benedictis, Diletta de

doi:10.1016/j.pcl.2008.10.013

Cited by 44 publications

(41 citation statements)

References 93 publications

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“…HRCT can detect bronchiectasis, centrilobular opacities (tree-in-bud), air trapping, and bronchial thickening. 63 Although not specific to aspiration, these findings are consistent with chronic aspiration.…”

Section: High-resolution Ct Scanmentioning

confidence: 54%

Oropharyngeal Dysphagia in Children

Durvasula

O’Neill

Richter

2014

Otolaryngologic Clinics of North America

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Section: High-resolution Ct Scanmentioning

confidence: 54%

Oropharyngeal Dysphagia in Children

Durvasula

O’Neill

Richter

2014

Otolaryngologic Clinics of North America

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“…1,2 However, little supportive evidence exists that the passage of acidic and/or bacteria-laden material into the respiratory tract causes clinically important disease. Descriptive case series [3][4][5] and studies that use subjective definitions of aspiration without radiographic confirmation have been reported in children.…”

mentioning

confidence: 99%

Infant Videofluoroscopic Swallow Study Testing, Swallowing Interventions, and Future Acute Respiratory Illness

Coon¹,

Srivastava

Stoddard

et al. 2016

Hospital Pediatrics

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OBJECTIVES: Tube feedings are commonly prescribed to infants with swallowing abnormalities detected by videofluoroscopic swallow study (VFSS), but there are no studies demonstrating efficacy of these interventions to reduce risk of acute respiratory illness (ARI). We sought to measure the association between swallowing interventions and future ARI, among VFSS-tested infants. METHODS: Retrospective cohort of all infants (<12 months) tested with VFSS at a children’s hospital between January 1, 2010, and January 1, 2012. Hospital ARI encounters (emergency, observation, or inpatient status) in a 22-hospital integrated health care delivery system, between the first VFSS and age 3 years, were measured. VFSS results were grouped by normal, intermediate, and oropharyngeal aspiration (OPA), with OPA further subdivided by silent versus cough and thin versus thick liquid OPA. Cox regression modeled the association between swallowing interventions (thickened or nasal tube feedings) and ARI, accounting for changes in swallowing and interventions over time. RESULTS: 576 infants were tested with a VFSS in their first year of life, receiving a total of 1051 VFSSs in their first 3 years of life. More than 60% of infants received a measured feeding intervention. With the exception of infants with silent OPA who received thickened feedings, neither thickening nor nasal tube feedings, compared with no intervention, were associated with a decreased risk of subsequent ARI. CONCLUSIONS: Swallowing interventions and repeated testing are common among VFSS-tested infants. However, the importance of diagnosing and intervening on VFSS-detected swallowing abnormalities for the majority of tested infants remains unclear.

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“…13,[33][34][35] Indirect neural reflexes with laryngospasm, bronchospasm, or apnea caused by esophageal acidification without aspiration. 9,11 Respiratory diseases may potentially exacerbate GER.…”

Section: Aspiration Through the Middlementioning

confidence: 99%