Aspiration Cytology of Normal Structures and Non-neoplastic Cysts of the Ovary

Kovacic, J; Rainer, S; Levičnik, Ana

doi:10.1007/978-1-4757-1767-9_27

Cited by 10 publications

(1 citation statement)

References 1 publication

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Another reason for the successful differentiation between the two groups could be represented by the similar fluid appearance of the two entities included in the benign group. The granulosa cells contained in FCs resemble macrophages [16], the latter being found in abundance in serous benign tumors [22]. Additionally, for a large proportion of both entities, a yellow fluid was described in the pathological analysis.…”

Section: Study Outcomesmentioning

confidence: 99%

Radiomic Analysis of MRI Images is Instrumental to the Stratification of Ovarian Cysts

Lupean

Ștefan

Feier

et al. 2020

JPM

View full text Add to dashboard Cite

The imaging diagnosis of malignant ovarian cysts relies on their morphological features, which are not always specific to malignancy. The histological analysis of these cysts shows specific fluid characteristics, which cannot be assessed by conventional imaging techniques. This study investigates whether the texture-based radiomics analysis (TA) of magnetic resonance (MRI) images of the fluid content within ovarian cysts can function as a noninvasive tool in differentiating between benign and malignant lesions. Twenty-eight patients with benign (n = 15) and malignant (n = 13) ovarian cysts who underwent MRI examinations were retrospectively included. TA of the fluid component was undertaken on an axial T2-weighted sequence. A comparison of resulted parameters between benign and malignant groups was undertaken using univariate, multivariate, multiple regression, and receiver operating characteristics analyses, with the calculation of the area under the curve (AUC). The standard deviation of pixel intensity was identified as an independent predictor of malignant cysts (AUC = 0.738; sensitivity, 61.54%; specificity, 86.67%). The prediction model was able to identify malignant lesions with 84.62% sensitivity and 80% specificity (AUC = 0.841). TA of the fluid contained within the ovarian cysts can differentiate between malignant and benign lesions and potentially act as a noninvasive tool augmenting the imaging diagnosis of ovarian cystic lesions.

show abstract

Section: Study Outcomesmentioning

confidence: 99%

Radiomic Analysis of MRI Images is Instrumental to the Stratification of Ovarian Cysts

Lupean

Ștefan

Feier

et al. 2020

JPM

View full text Add to dashboard Cite

show abstract

Cytology of nonneoplastic cysts of the ovary

Selvaggi

1990

Diagnostic Cytopathology

View full text Add to dashboard Cite

From March 1986 through September 1988, cytologic material from 13 nonneoplastic ovarian cysts collected at the time of surgical removal of the ovary was compared with the histologic follow-up of these lesions in an attempt to characterize the cytologic features of benign ovarian cysts. In 22 additional nonneoplastic cysts, cellular material was obtained by the clinician with fine-needle aspiration. The 32 patients ranged in age from 18 to 64 yr (mean, 36.8; median, 35.5); of these, 24 were premenopausal, 6 were perimenopausal, and 2 were postmenopausal. Cytologically, follicular cysts (two cases) showed clusters of granulosa cells, some containing mitotic figures. Luteinized follicular cysts (11 cases) were composed of granulosa cells admixed with luteinized granulosa cells. Hemorrhagic corpora lutei (five cases) were characterized by fresh blood containing hemosiderin-laden macrophages and luteinized granulosa cells. Hemorrhagic corpus luteal cysts (10 cases) showed the presence of luteinized granulosa cells, fibroblasts, hemosiderin-laden macrophages, fresh blood, and abundant fibrin. In addition to these findings, regressing corpora lutei (two cases) contained macrophages with yellow hematoidin pigment. Endometriotic cysts (three cases) were composed of fresh blood, hemosiderin-laden macrophages, and scattered endometrial cells. In two cysts, subclassification was not possible due to scanty cellularity. An understanding of the cytologic features of nonneoplastic ovarian cysts may encourage aspiration as opposed to surgical ovarian removal. This has important implications, particularly in women of child-bearing age who wish to preserve their fertility.

show abstract

Cellular follicular cyst of the ovary: Fluid cytology mimicking malignancy

Stanley

Horwitz

Frable

1991

Diagnostic Cytopathology

View full text Add to dashboard Cite

We report three ovarian cysts studied by aspiration cytology. The fluids obtained were highly cellular, with numerous groups of atypical cells featuring a high nuclear-cytoplasmic ratio, nuclear hyperchromasia, and prominent nucleoli. In each case, these features were considered evidence of a low-grade malignant neoplasm. All three patients underwent oophorectomy, which revealed benign follicular cysts. Possible means of resolving the diagnostic dilemma posed by these cellular follicular cysts are discussed.

show abstract

Aspiration Cytology of Normal Structures and Non-neoplastic Cysts of the Ovary

Cited by 10 publications

References 1 publication

Radiomic Analysis of MRI Images is Instrumental to the Stratification of Ovarian Cysts

Radiomic Analysis of MRI Images is Instrumental to the Stratification of Ovarian Cysts

Cytology of nonneoplastic cysts of the ovary

Cellular follicular cyst of the ovary: Fluid cytology mimicking malignancy

Contact Info

Product

Resources

About