Aspiration Cytology in the Diagnosis of Primary Tumors of Skin Adnexa

Rege, Jyoti; Shet, Tanuja

doi:10.1159/000328293

Cited by 34 publications

(42 citation statements)

References 13 publications

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“…clusters of epithelial cells, myoepithelial cells and a chondromyxoid ground substance. The epithelial cells are small and had nuclei with finely dispersed chromatin and scant cytoplasm [14,15]. Similar cytological features were also noted in our study.…”

Section: Discussionsupporting

confidence: 85%

“…Similar cytological features were also noted in our study. According to Rege and Shet [14] the aspirates in both of their cases resembled those of pleomorphic adenoma of the salivary gland. We observed a similar type of aspirate in all 4 of our cases.…”

Section: Discussionmentioning

confidence: 99%

“…The cytology of pilomatrixoma and proliferating trichilemmal cyst has been described in the literature, while that of trichilemmoma has not been reported. According to Rege and Shet [14], cytologically, this group of tumors reveals basaloid cells with a variable amount of other cells and constituents. …”

Section: Discussionmentioning

confidence: 99%

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Diagnostic Evaluation of Skin Adnexal Tumors by Fine-Needle Aspiration Cytology

Chand

Khare²,

Gupta³

et al. 2016

Acta Cytologica

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Background: The diagnosis of skin adnexal tumors is usually based on histopathology. However, fine-needle aspiration cytology (FNAC) can be of great help and shows a high degree of correlation to the final diagnosis. It is helpful in many situations where skin lesions are a manifestation of certain systemic syndromes and aids to the formation of precise treatment plans. Materials and Methods: This prospective study was carried out to assess the diagnosis of skin adnexal tumors based on FNAC and their comparison with histopathological diagnoses. There were 14 patients with FNAC and histopathological follow-up in whom a final diagnosis of skin adnexal tumor was made. The results of FNAC were compared with histopathological diagnoses for complete correlation, partial correlation (cases where an FNAC diagnosis of skin adnexal tumor was made but a precise diagnosis of the subtype was not possible) or no correlation (where FNAC failed to diagnose a skin adnexal tumor). Results: Among the 14 cases of skin adnexal tumor, there was total correlation between the FNAC diagnosis and final histopathological diagnosis in 8 cases (57.1%) and a partial correlation in 4 cases (28.5%). There was no correlation of the FNAC diagnosis with the histopathological diagnosis in only 2 cases (14.3%). Conclusions: FNAC is very useful in making a diagnosis of skin adnexal tumors and helps in the management of the patient.

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Section: Discussionsupporting

confidence: 85%

Section: Discussionmentioning

confidence: 99%

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Diagnostic Evaluation of Skin Adnexal Tumors by Fine-Needle Aspiration Cytology

Chand

Khare²,

Gupta³

et al. 2016

Acta Cytologica

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“…Pilar cysts can also give rise to proliferating trichilemmal cysts and pilar tumors. 4,6,9 Thus, if aware of the cytologic features of pilar cysts, a cytologist can check for the above possibilities.…”

Section: Discussionmentioning

confidence: 99%

Cytodiagnosis of Simple and Proliferating Trichilemmal Cysts

Shet

Rege²,

Naik³

2001

Acta Cytologica

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“…Glycogen is demonstrated in the cytoplasm of some of the clear cells. It lacks Comedone reaction (which is a feature of sebaceous gland tumor) and Decapitation reaction (which is a feature of Apocrine gland tumor) [7]. Hence eccrine carcinoma is a diagnosis of exclusion after ruling out sebaceous gland tumor and apocrine gland tumor.Ki-67 and p53 staining may be useful histologic parameters.…”

Section: Discussionmentioning

confidence: 99%

Malignant Adnexal Tumour—Eccrine Hidradeno Carcinoma a Case Report

Kishore

2014

Indian J Surg Oncol

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A 55 year old male patient presented with an ulceroproliferative lesion over the left thigh with left inguinal lymphadenopathy (Fig. 1a). Clinically it was suspected to be squamous cell carcinoma with inguinal lymphnode metastasis. Wedge biopsy of the lesion and fine needle aspiration cytology of the inguinal node (Fig. 3a) surprisingly revealed it to be Malignant adnexal tumour of skin with inguinal node metastasis. High frequency ultrasound scan and computed tomography revealed a malignant mass lesion in the subcutaneous plane of left thigh with left superficial inguinal lymphnode enlargement. Metastatic work up was done with base line chest X-ray and MRI abdomen and pelvis. Patient was treated with wide local excision ( Fig. 1b) with left sided ilio-inguinal block dissection ( Fig. 2a-d). Histopathology showed normal skin lined by stratified squamous epithelium ( Fig. 3b) with neoplastic cells in the deeper levels arranged in nests which are tightly surrounded by fibrous septa (Fig. 3c) with infiltration into cutaneous vasculature . The neoplastic cells having scant to moderate amount of cytoplasm and the nuclei showing atypia and hyperchromatism, some showing prominent nucleoli. There is absence of decapitation reaction or comedone reaction (Fig. 3d). Based on the histologic features a final diagnosis of Malignant adnexal tumor of Eccrine differentiation (Hidradeno carcinoma) was made. All circumferential and deep resected margins free of tumor and 7/16 nodes showed metastatic deposits. Then the patient was subjected to post operative radiotherapy (70 Gy for primary field and 50 Gy for the inguinal region). The patient was followed up thrice a year with proper clinical examination. MRI of the left thigh and pelvis and chest X-ray after a year showed no evidence of recurrence. The patient is still in follow up for more than 20 months and is in good control of the disease.

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Aspiration Cytology in the Diagnosis of Primary Tumors of Skin Adnexa

Cited by 34 publications

References 13 publications

Diagnostic Evaluation of Skin Adnexal Tumors by Fine-Needle Aspiration Cytology

Diagnostic Evaluation of Skin Adnexal Tumors by Fine-Needle Aspiration Cytology

Cytodiagnosis of Simple and Proliferating Trichilemmal Cysts

Malignant Adnexal Tumour—Eccrine Hidradeno Carcinoma a Case Report

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