Aspiration Complicating Bronchopulmonary Dysplasia

Radford, Peggy; Stillwell, Paul C.; Blue, Barbara; Hertel, Grant

doi:10.1378/chest.107.1.185

Cited by 48 publications

(28 citation statements)

References 10 publications

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“…24 The use of anti-reflux medications increased over time, but was not significantly different between groups. This finding concurs with a study by Radford et al 25 that indicated that gastroesophageal reflux is more common in infants with BPD. An advantage of using a 30 kcal/oz formulation also may be the provision of a lower volume of milk while continuing to meet nutrient needs.…”

Section: Discussionsupporting

confidence: 93%

Clinical Experience in Enteral Nutrition Support for Premature Infants With Bronchopulmonary Dysplasia

Puangco

Schanler

2000

J Perinatol

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Section: Discussionsupporting

confidence: 93%

Clinical Experience in Enteral Nutrition Support for Premature Infants With Bronchopulmonary Dysplasia

Puangco

Schanler

2000

J Perinatol

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“…This study provides the first reference values for lipidladen macrophages obtained by bronchoalveolar lavage (4) Cystic fibrosis (3) Undescended testis (4) Exogenous allergic alveolitis (1) Hypertrophy of adenoids (3) Bronchiolitis obliterans (1) Vesicoureteral reflux (1) Idiopathic pulmonary hemosiderosis (1) Chronic otitis (1) in children without lung disease. LLM indices in our population of children without pulmonary disease are higher than those reported for healthy adults.…”

Section: Discussionmentioning

confidence: 99%

“…[1][2][3][4] Diagnostic procedures to verify aspiration include barium swallow, chest X-ray, colloid scintigraphy, 5 12-24 h monitoring of esophageal pH, and esophagogastroduodenoscopy. 6 None of these methods has been shown to be sensitive or specific for pulmonary aspiration, and a gold standard for the diagnosis of aspiration is still lacking.…”

Section: Introductionmentioning

confidence: 99%

Lipid-laden macrophages in bronchoalveolar lavage fluid as a marker for pulmonary aspiration

Knauer-Fischer¹,

Ratjen²

1999

Pediatr. Pulmonol.

128

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“…4 The risk of decreased pulmonary function and aspiration with GERD is increased in infants with conditions such as cystic fibrosis and bronchopulmonary dysplasia. 29,31 GERD is frequently cited as a cause of apnea. 6,13,44 …”

Section: Clinical Manifestations Of Gerdmentioning

confidence: 99%

Discerning Differences

Henry

2004

Advances in Neonatal Care

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Gastroesophageal reflux (GER) is a frequently encountered problem in infancy; it commonly resolves spontaneously by 12 months of age. Caregivers are challenged to discriminate between physiologic GER and the much less common and more serious condition of pathologic gastroesophageal reflux disease (GERD). Pathologic GERD may require more extensive clinical evaluation and necessitate treatment. GERD may be primary or secondary; secondary GERD is associated with a number of genetic syndromes, chromosomal abnormalities, birth defects, or a host of neurologic conditions frequently seen in the newborn intensive care unit. This article reviews the unique anatomic, physiologic, developmental, and nutritional vulnerabilities of infants that make them susceptible to GER and GERD. The North American Society of Pediatric Gastroenterology and Nutrition have recently developed a comprehensive evidence-based clinical practice guideline that structures the diagnostic approach and treatment option in infants with suspected and confirmed GERD. These guidelines provide clear definitions of GER and GERD to aid the clinician in distinguishing between the 2 conditions. They emphasize the use of history and physical examination and discuss the indications for the use of other diagnostic procedures, such as upper gastrointestinal studies, nuclear medicine scintiscan, esophagogastroduodenoscopy with biopsy, and esophageal pH probe monitoring. Management of GERD begins with a nonpharmacologic approach; the emphasis is on positioning, a trial of a hypoallergenic formula, and thickening of feedings. When these measures fail to control symptoms, a trial of either histamine(2) antagonists or a proton pump inhibitor may be indicated. Finally, surgical treatment may be needed if all other management measures fail. New sleep recommendations for infants with GERD are now consistent with the American Academy of Pediatrics' standard recommendations. Prone sleep positioning is only considered in unusual cases, where the risk of death and complications from GERD outweighs the potential increased risk of sudden infant death syndrome (SIDS). The nursing care of infants with GER and GERD, as well as relevant issues for parent education and support, are reviewed and are essential elements in managing this common condition.

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Aspiration Complicating Bronchopulmonary Dysplasia

Cited by 48 publications

References 10 publications

Clinical Experience in Enteral Nutrition Support for Premature Infants With Bronchopulmonary Dysplasia

Clinical Experience in Enteral Nutrition Support for Premature Infants With Bronchopulmonary Dysplasia

Lipid-laden macrophages in bronchoalveolar lavage fluid as a marker for pulmonary aspiration

Discerning Differences

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