1999
DOI: 10.1159/000007672
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Aspiration: A Possible Severe Complication in Colonoscopy Preparation of Elderly People by Orthograde Intestine Lavage

Abstract: Total gut lavage is a widely recommended method in preparation for colonoscopy and there are almost no reports of severe complications in the literature. Application of orthograde lavage by a nasogastric tube may be necessary in disorientated patients, assisted by slight medical sedation, if necessary. Despite absolutely correct appliance of the method, a case of severe aspiration with subsequent hypoxemia and stroke in a senile female patient, suffering from a common hiatal hernia, is described.

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Cited by 23 publications
(16 citation statements)
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“…87 Rare adverse events in patients receiving PEG have been reported and include nausea with and without vomiting, abdominal pain, pulmonary aspiration, Mallory-Weiss tear, PEG-induced pancreatitis and colitis, lavage-induced pill malabsorption, cardiac dysrhythmia, and the syndrome of inappropriate antidiuretic hormone. 2,[88][89][90] An increase in plasma volume has been shown to occur in some individuals with concomitant disease states that predispose them to fluid retention. 91,92 Adverse effects may occur less frequently in association with preparation regimens that use a reduced volume of PEG.…”
Section: Safetymentioning
confidence: 99%
“…87 Rare adverse events in patients receiving PEG have been reported and include nausea with and without vomiting, abdominal pain, pulmonary aspiration, Mallory-Weiss tear, PEG-induced pancreatitis and colitis, lavage-induced pill malabsorption, cardiac dysrhythmia, and the syndrome of inappropriate antidiuretic hormone. 2,[88][89][90] An increase in plasma volume has been shown to occur in some individuals with concomitant disease states that predispose them to fluid retention. 91,92 Adverse effects may occur less frequently in association with preparation regimens that use a reduced volume of PEG.…”
Section: Safetymentioning
confidence: 99%
“…The remaining 8 patients (cases 5-12; age 5-86 years) did not have radiographic evidence of the location of the nasogastric tube at any time. [8][9][10][11][12][13][14][15] Pulmonary complications from the PEG-ES infusions contributed to the death of 5 of these patients (cases 6-10).…”
Section: Resultsmentioning
confidence: 99%
“…Fluid withdrawn from the nasogastric tube in case 7 was described as "acidic." 10 Although an aspirate with a low pH most likely rules out respiratory placement, it cannot rule out esophageal placement, given that fluid withdrawn from the esophagus could be refluxed acidic gastric contents. 18,19 Signs of gastrointestinal intolerance were observed in multiple cases; for example, vomiting occurred in 6 patients (cases 2, 3, 6, 10, 11, and 12) before development of respiratory symptoms.…”
Section: Commentsmentioning
confidence: 99%
“…In elderly patients or patients whose medical conditions prevent oral administration, nasogastric administration may be required. Caution and vigilance must be taken to ensure that the tube is properly positioned and that the patient is closely monitored, because aspiration may result in fatal complications [34].…”
Section: Cleansing Regimensmentioning
confidence: 99%