Aspergillus oryzae Grown on Rice Hulls Used as an Additive for Pretreatment of Starch-Containing Wastewater from the Pulp and Paper Industry

Costa, Stefania; Summa, Daniela; Zappaterra, Federico; Blo, Riccardo; Tamburini, Elena

doi:10.3390/fermentation7040317

Cited by 7 publications

(2 citation statements)

References 23 publications

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“…A strain of Aspergillus oryzae that is safe to use and widely used in the brewing [1,2], enzyme [3,4], and waste treatment [5,6] industries is photoresponsive to different light wavelengths and intensities [7][8][9][10]. Our earlier investigation demonstrated that A. oryzae GDMCC 3.31 is more sensitive to CBL (475 nm) than to red light (630 nm) [11].…”

Section: Introductionmentioning

confidence: 96%

Effects of Pulsed Light on Mycelium Growth and Conidiation in Aspergillus oryzae

Lin

Jiang

et al. 2023

Fermentation

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Understanding how Aspergillus oryzae responds to light is critical for developing efficient light regulation strategies in the brewing and waste treatment industries. Although continuous light is known to restrict A. oryzae, little is known about A. oryzae’s sensitivity to light with photoperiod. In this study, we used pulse wave modulation (PWM) to generate nine pulsed blue light (PBL) treatments with varying peak light intensities and frequencies. The effect of PBL on A. oryzae was then compared to that of continuous blue light (CBL). Our findings showed that A. oryzae GDMCC 3.31 mycelium developed faster and produced more conidia under PBL with specific peak intensities and frequencies than under CBL treatment when the light dose and average light intensity were held constant. The colony diameter and conidia count under the two PBL treatments (PL-20_40%_1 Hz and PL-400_20%_10 kHz) were 1.13 and 1.22 times greater than under the CBL treatments, respectively. This different response may be mainly attributed to A. oryzae’s adaptation to the light–dark cycles in nature. Furthermore, an interactive effect was found between peak light intensity and frequency. This work includes pulsed wave modulation as a new factor that influences the A. oryzae photoresponse and recommends it in the development of light regulation methods for fermentation.

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Section: Introductionmentioning

confidence: 96%

Effects of Pulsed Light on Mycelium Growth and Conidiation in Aspergillus oryzae

Lin

Jiang

et al. 2023

Fermentation

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“…For the synthesis of the ibuprofen esters, we decided to embark on the path of chemical modifications mediated by pathways with biological origins, also called biotransformation. These biochemical transformations can be achieved by exploiting whole cells (bacteria [18] or fungi [19]), their lysate, or isolated enzymes [20]. The latter allows for the synthesis of prodrugs through straightforward synthetic pathways, characterized as cheaper, less energy-consuming, and more selective compared to the canonical chemical modifications.…”

Section: Introductionmentioning

confidence: 99%

Biocatalytic Insights for The Synthesis of New Potential Prodrugs: Design of two Ibuprofen Derivatives

Zappaterra,

Presini,

Venturi

et al. 2023

Applied Sciences

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Due to its effectiveness, ibuprofen is one of the most popular anti-inflammatory drugs worldwide. However, the poor water solubility of this active ingredient severely limits its spectrum of pharmaceutical formulations (and often results in severe adverse effects due to high administered doses). To overcome these limitations, in this work, we enzymatically synthesized more hydrophilic derivatives of ibuprofen through its covalent attachment to two biobased polyalcohols: erythritol and glycerol. Herein, we report the optimized reaction conditions to produce an IBU–erythritol ester (82% ± 4% of conversion) by using Candida antarctica lipase B (CalB). Furthermore, we also report the enantioselective solventless esterification of (S)-ibuprofen with glycerol (83% ± 5% of conversion), exploiting immobilized Rhizomucor miehei lipase as a biocatalyst. The full NMR characterizations of the prodrug esters were performed via 1H, 13C-NMR, DEPT, COSY, HSQC, and HMBC-NMR. The approach reported in this work can be extended to a large variety of poorly water-soluble active pharmaceutical ingredients (APIs).

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Optimization of Fermentative Parameters for Hyperproduction of Protease from Aspergillus viridi using Lignocellulosic Byproducts as Sole Substrate

Nadeem,

Tayyab,

Mehmood

et al. 2024

Waste Biomass Valor

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Aspergillus oryzae Grown on Rice Hulls Used as an Additive for Pretreatment of Starch-Containing Wastewater from the Pulp and Paper Industry

Cited by 7 publications

References 23 publications

Effects of Pulsed Light on Mycelium Growth and Conidiation in Aspergillus oryzae

Effects of Pulsed Light on Mycelium Growth and Conidiation in Aspergillus oryzae

Biocatalytic Insights for The Synthesis of New Potential Prodrugs: Design of two Ibuprofen Derivatives

Optimization of Fermentative Parameters for Hyperproduction of Protease from Aspergillus viridi using Lignocellulosic Byproducts as Sole Substrate

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