Aspergillus fumigatus spondylodiscitis with bilateral psoas abscess in a renal transplant patient with pulmonary tuberculosis : A rare case report

Abstract

Background: Aspergillus spondylodiscitis is increasingly described in immune-compromised patients. Its diagnosis is challenging and its delay results in high mortality and morbidity in view of its relative infrequency and the non-specific clinical signs and symptoms. Case report:We report a case of thoracic spondylodiscitis caused by Aspergillus fumigatus in a patient of renal transplantation and with proven pulmonary tuberculosis. Conclusion:We reiterate that transplantist and the treating physician should have high grade of suspicion for the invasive Aspergillosis even when the patient complains of vague non-specific back pain, and aggresively aim to rule out fungal infection. Early surgical debridement and antifungal therapy to be executedto prevent rapid progression of invasive aspergillosis and neurological damage.

Primary spinal infections in patients with solid organ transplant: a systematic literature review and illustrative case

“…4). Upon careful review, 13 articles published between 2010 and 2018 met the studies inclusion/exclusion criteria, [16][17][18][19][20][21][22][23][24][25][26][27][28] including 2 case series, 10 case reports, and 1 case-control study (Table 1). These studies featured a total of 67 patients, of whom 40 met inclusion criteria (mean age, 47 years; range, 17 to 80 years; 67.8% males).…”