Aspergillosis and the Aspergilli

Broncho-pulmonary Aspergillosis : A Review and a Report of Eight New Cases

“…Numerous large hyphae and spores were seen, and on culture A. fumigatus, but no other organism, was grown. Cawley (1947) reported multiple mycotic abscesses y due to A. fumigatus in the lungs of a child at necropsy, and Cooper (1946) and Duncan (1945) found similar abscesses in adults.…”

“…Recently it has been suggested that such superinfection may occur following treatment with antibiotics in large and prolonged dosage (Abbott, Fernando, Gurling, and Meade, 1952). It seems that this clinical picture of invasion of lungs and other organs may occur as a primary manifestation of aspergillosis without underlying disease (Duncan, 1945;Cooper, 1946;Cawley, 1947;Hertzog and others, 1949;Grekin, Cawley, and Zheutlin, 1950).…”

Disseminated Aspergillosis and Moniliasis Associated with Agranulocytosis and Antibiotic Therapy

“…H. G. Close, personal communication). Very widespread dissemination has been described (Cawley, 1947;Grekin et al, 1950), as have two cases of endocarditis (Zimmerman, 1950). Infection of the mouth and alimentary tract with monilia is a common complication of agranulocytosis.…”

“…The portal of entry may be the alimentary tract, as in the present case and in those of Lederer and Todd (1949). Duhig and Mead (1951) discussed the possibility of introduction into the blood stream during intravenous therapy. This probably occurred in the cases described by Joachim and Polayes (1940) and Wikler et al (1942) in drug addicts, and by Geiger et al (1945).…”

Pulmonary Aspergillosis Following Post-influenzal Bronchopneumonia Treated with Antibiotics

“…Sometimes a blood-borne dissemination gives rise to endocarditis, grapulomatous lesions in many organs, meningitis, and even brain abscess (Geiger et al, 1945;Cawley, 1947;Grekin et al, 1950).…”