Aspergillose sphénoïdale révélée par des signes neuro-ophtalmologiques : à propos d’un cas

Management of Isolated sphenoidal aspergillosis: Case report and review of literature

“…On the other hand, many authors have identified a set of risk factors and predisposing medical disease which associated to developing sphenoid aspergillosis more than others, such as patients having allergy, alcoholism, long-term corticosteroid therapy, diabetes, AIDS, the use of anti-tuberculosis drugs or following solid organ transplantation [ 2 , 3 ].…”

“…As for ophthalmological signs, mainly explained by orbital extension and cavernous sinus invasion, they are often observed in association with invasive forms [ 2 , 3 ]. They are reported to be the second most common complex symptom in sphenoid diseases.…”

“…Radiologically, the standard images appear normal they are currently neglected in terms of invasive sinusitis [ 2 ]. Indeed CT scan and MRI represent the most sensitive diagnostic means to highlight an Aspergillus sinusitis by demonstrating ferromagnetic substances [ 10 ].…”

“…We need CT in axial and coronal sections 3 mm thick [ 3 ]. The most characteristic aspect is the presence of a total filling of the sinus by dense, non-raising material after injection of iodine and comprising a calcium or metal density image corresponding to calcium salts and other heavy metals (lead, copper, iron, manganese) produced by mycosis [ 2 , 7 ]. This aspect was found in our patient.…”

“…Sphenoidal aspergillosis is a rare disease whose incidence is estimated at 1.2 % per year [ 1 ]. This incidence has undergone an increase in the last decade, due to an epidemiological shift towards fungal infections, and this, in front of the use of antibiotics, corticosteroids, and the development of diagnostic means [ 2 ]. Besides, this entity could be probably underestimated due to the lack of systematic mycological sampling and anatomopathological study [ 3 ].…”