Aspekte zum Trauma des Innenohrs im Rahmen der CI-Versorgung

Klenzner, Thomas

doi:10.1007/s00106-011-2288-x

Cited by 2 publications

(1 citation statement)

References 24 publications

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“…Future inner ear surgery will require a highly precise and most atraumatic surgical approach to the human cochlea with the organ of hearing. This is mandatory to give the possibility for future treatment options for diseases of the inner ear, for example, to place devices like drug delivery systems, electrodes, or optical fibers with preservation of existing inner ear function such as hearing or balance [1–3]. As an important surgical step, cochleostomy provides the surgical approach to the human cochlea when a round window approach is inconvenient or impossible, enabling the implantation of intracochlea devices.…”

Section: Introductionmentioning

confidence: 99%

Optical Coherence Tomography Guided Laser Cochleostomy: Towards the Accuracy on Tens of Micrometer Scale

Zhang¹,

Pfeiffer

Weller

et al. 2014

BioMed Research International

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Lasers have been proven to be precise tools for bone ablation. Applying no mechanical stress to the patient, they are potentially very suitable for microsurgery on fragile structures such as the inner ear. However, it remains challenging to control the laser-bone ablation without injuring embedded soft tissue. In this work, we demonstrate a closed-loop control of a short-pulsed CO2 laser to perform laser cochleostomy under the monitoring of an optical coherence tomography (OCT) system. A foresighted detection of the bone-endosteum-perilymph boundary several hundred micrometers before its exposure has been realized. Position and duration of the laser pulses are planned based on the residual bone thickness distribution. OCT itself is also used as a highly accurate tracking system for motion compensation between the target area and the optics. During ex vivo experimental evaluation on fresh porcine cochleae, the ablation process terminated automatically when the thickness of the residual tissue layer uniformly reached a predefined value. The shape of the resulting channel bottom converged to the natural curvature of the endosteal layer without injuring the critical structure. Preliminary measurements in OCT scans indicated that the mean absolute accuracy of the shape approximation was only around 20 μm.

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Section: Introductionmentioning

confidence: 99%

Optical Coherence Tomography Guided Laser Cochleostomy: Towards the Accuracy on Tens of Micrometer Scale

Zhang¹,

Pfeiffer

Weller

et al. 2014

BioMed Research International

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Optical coherence tomography as highly accurate optical tracking system

Zhang

Wörn

2014

2014 IEEE/ASME International Conference on Advanced Intelligent Mechatronics

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Optical coherence tomography (OCT) guided laser cochleostomy enables the ablation accuracy on tens of micrometer scale and therefore also requires a high patient tracking accuracy on the same order of magnitude, which however exceeds the ability of the conventional optical or electromagnetic tracking systems. We have developed a novel approach of using OCT itself as a highly accurate optical tracking system by ablating tiny artificial landmarks surrounding the cochleostomy on the target bone surface and locating them in the online acquired 3D OCT Volumes. The mechanism enables a direct tracking of the target area with respect to the laser optics while the conventional systems rely on indirect tracking of the markers or sensors attached to the regions of interest. The new approach has achieved an overall tracking accuracy of 22.8±14.9μm (mean absolute error) and 27.2μm (root mean square), which is one order of magnitude higher than the conventional tracking system-based setups. ). the online measured residual bone thickness and enables the ablation accuracy on tens of micrometer scale.

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Aspekte zum Trauma des Innenohrs im Rahmen der CI-Versorgung

Cited by 2 publications

References 24 publications

Optical Coherence Tomography Guided Laser Cochleostomy: Towards the Accuracy on Tens of Micrometer Scale

Optical Coherence Tomography Guided Laser Cochleostomy: Towards the Accuracy on Tens of Micrometer Scale

Optical coherence tomography as highly accurate optical tracking system

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