Aspectos clínicos, epidemiológicos e patológicos da infecção natural em bovinos por Trypanosoma vivax na Paraíba

Batista, Jael Soares; Bezerra, Francisco Silvestre Brilhante; Lira, Rodrigo Araújo; Carvalho, José Ricardo Gomes de; Neto, Antonio M. Rosado; Petri, Alinson A.; Teixeira, Marta Maria Geraldes

doi:10.1590/s0100-736x2008000100010

Cited by 54 publications

(54 citation statements)

References 16 publications

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“…Decreases in erythrocytes have been associated with erythrocytes desialylation in the acute phase of disease, stage of high parasitemia (GUEGAN et al, 2013). Our findings differ from those obtained by other authors in cattle BATISTA et al, 2007BATISTA et al, , 2008CUGLOVICI et al, 2010;CADIOLI et al, 2012) who noticed moderate to severe anemia. However, Schenk et al (2001) observed a PCV decrease similar to our study, that reached a minimum value of 25% at 10 DAI and this variable did not return to pre-infection values.…”

Section: Discussioncontrasting

confidence: 92%

“…Clinical signs presented by the animals of this study were consistent with those reported by other authors (BATISTA et al, 2008;CADIOLI et al, 2012), consisting principally of apathy, enlarged lymph nodes, hyporexia, weight loss, diarrhea, submandibular edema and vaginal discharge, all mild to moderate degree. The animal's susceptibility to infection is associated with several factors such as age, concurrent infections, pregnancy, lactation and nutritional conditions (KATUNGUKA-RWAKISHAYA et al, 1997).…”

Section: Discussionsupporting

confidence: 91%

“…In cattle, T. vivax unleashes unspecific signs such as fever, anorexia, weight loss, reduced milk yield, enlarged lymph nodes, abortion and diarrhea (BATISTA et al, 2008;CADIOLI et al, 2012) as well as anemia (SCHENK et al, 2001), leukopenia (SILVA et al, 1999) and eventual leukocytosis (CADIOLI et al, 2012). The biochemical profile of animals infected by T. vivax are usually normal (SCHENK et al, 2001;ALMEIDA et al, 2010).…”

Section: Introductionmentioning

confidence: 99%

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Evaluation of clinical signs, parasitemia, hematologic and biochemical changes in cattle experimentally infected with Trypanosoma vivax

Fidélis

Sampaio

Machado

et al. 2016

Rev. Bras. Parasitol. Vet.

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Infections by Trypanosoma vivax cause great losses to livestock in Africa and Central and South Americas. Outbreaks due this parasite have been occurred with increasing frequency in Brazil. Knowledge of changes caused by T. vivax during the course of this disease can be of great diagnostic value. Thus, clinical signs, parasitemia, hematologic and biochemical changes of cattle experimentally infected by this hemoparasite were evaluated. Two distinct phases were verified during the infection -an acute phase where circulating parasites were seen and then a chronic phase where fluctuations in parasitemia were detected including aparasitemic periods. A constant reduction in erythrocytes, hemoglobin and packed cell volume (PVC) were observed. White blood cells (WBC) showed pronounced changes such as severe neutropenia and lymphopenia during the acute phase of the illness. Decreases in cholesterol, albumin, aspartate aminotransferase (AST), lactate dehydrogenase (LDH), and increases in glucose, globulin, protein, and alkaline phosphatase (ALP) were observed. The "Lins" isolate of T. vivax showed pathogenicity for cattle, and intense parasitemia was detected in the early stages of infection. Circulating parasites were detected for about two months. The most evident laboratory abnormalities were found in WBC parameters, including thrombocytopenia.Keywords: Trypanosomiasis, bovine, host-parasite relationship, complete blood count. ResumoInfecções pelo Trypanosoma vivax causam grandes prejuízos à pecuária na África e Américas Central e do Sul. Surtos devido a este protozoário têm ocorrido com frequência cada vez maior no Brasil. O conhecimento das alterações provocadas pelo T. vivax durante a evolução desta enfermidade podem ser de grande valia para o auxílio no diagnóstico. Para tanto foram estudados os sinais clínicos, parasitemia, alterações hematológicas e bioquímicas em bovinos experimentalmente infectados por este hemoparasito. Foram verificadas duas fases distintas durante a infecção, uma aguda onde parasitos circulantes foram vistos durante todo o período, e posteriormente uma crônica, onde foram detectadas flutuações na parasitemia, com períodos aparasitêmicos. Foi verificada constante diminuição da contagem global de eritrócitos, teor de hemoglobina e volume globular (VG). O leucograma revelou leucopenia por neutropenia e linfopenia durante a fase aguda da enfermidade. Foram observados diminuição do colesterol, albumina, aspartato aminotransferase (AST), lactato desidrogenase (LDH) e aumento da glicose, globulinas, proteínas e fosfatase alcalina (FA). O isolado "Lins" de T. vivax apresentou patogenicidade para bovinos, verificando-se parasitemia intensa nos estágios iniciais da infecção, sendo detectados parasitas circulantes por aproximadamente dois meses. As alterações laboratoriais mais evidentes foram encontradas nos parâmetros do leucograma, ainda destacando-se um quadro de trombocitopenia.Palavras-chave: Tripanossomíase, bovino, relação parasita-hospedeiro, hemograma.

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Section: Discussioncontrasting

confidence: 92%

Section: Discussionsupporting

confidence: 91%

Section: Introductionmentioning

confidence: 99%

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Evaluation of clinical signs, parasitemia, hematologic and biochemical changes in cattle experimentally infected with Trypanosoma vivax

Fidélis

Sampaio

Machado

et al. 2016

Rev. Bras. Parasitol. Vet.

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“…While the origin of the first outbreak in 2002 remains unknown, the subsequent two outbreaks (2005 and 2006) were associated with cattle movements among these farms (BATISTA et al, 2008). These outbreaks occurred in the north of the state of Paraíba, approximately 70 km from the nearest farms sampled in the present study, which were located in the municipalities of Sousa and São José do Espinharas.…”

Section: Discussionmentioning

confidence: 75%

“…These flies have also been incriminated as mechanical vectors for A. marginale (HAWKINS et al, 1982;KESSLER, 2001). In Brazil, T. vivax has been sporadically reported infecting ruminants, as recently reported in three outbreaks affecting cattle in the semiarid region of the State of Paraíba (BATISTA et al, 2007(BATISTA et al, , 2008.…”

Section: Introductionmentioning

confidence: 90%

Seroprevalence and risk factors for cattle anaplasmosis, babesiosis, and trypanosomiasis in a Brazilian semiarid region

Costa

Ribeiro

Duarte

et al. 2013

Rev. Bras. Parasitol. Vet.

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The seroprevalence of Anaplasma marginale, Babesia bigemina, Babesia bovis and Trypanosoma vivax and the risk factors for these infections were investigated in 509 cows on 37 farms in the semiarid region of Paraíba, northeastern Brazil. Cow serum samples were tested by means of immunofluorescence assay (IFA) against each specific antigen. The mean seroprevalence values per farm were 15.0% (range: 0-75%) for A. marginale, 9.5% (range: 0-40%) for B. bigemina and 26.9% (range: 0-73.7%) for B. bovis. All cows tested negative for T. vivax. Higher prevalence for A. marginale was significantly associated with less frequent acaricide spraying per year and with higher use of injectable antihelminthics. Presence of cows positive for B. bigemina was significantly associated with acaricide use and with presence of horse flies on the farm. Both occurrence and higher prevalence of B. bovis were significantly associated with recent observations of ticks on cattle. Overall, the present results indicate that the region investigated is an enzootically unstable area for A. marginale, B. bigemina and B. bovis, since most animals were seronegative to at least one agent.Keywords: Anaplasma marginale, Babesia bigemina, Babesia bovis, cattle, risk factors, Brazil. ResumoA soroprevalência de Anaplasma marginale, Babesia bigemina, Babesia bovis e Trypanosoma vivax, assim como os fatores de risco para estas infecções, foram investigadas em 37 fazendas (total de 509 vacas) da região semiárida da Paraíba, nordeste do Brasil. A presença de anticorpos nos soros dos animais foi detectada pela técnica de imunofluorescência indireta, utilizando antígenos específicos. Os valores médios de soroprevalência por fazenda foram 15,0% (0-75%) para A. marginale, 9,5% (0-40%) para B. bigemina, e 26,9% (0-73,7%) para B. bovis. Todas as vacas foram soronegativas para T. vivax. As maiores prevalências de A. marginale foram significativamente associadas com menor uso de carrapaticidas por ano e com uso mais frequente de antihelmínticos injetáveis. A soroprevalência de B. bigemina foi significativamente associada com o uso de carrapaticidas, e com a presença de mutucas na fazenda. Tanto a ocorrência como a maior soroprevalência para B. bovis nas fazendas foram significativamente associadas com a presença recente de carrapatos nos bovinos. No geral, os resultados indicam que as fazendas amostradas estão situadas em área de instabilidade enzoótica para A. marginale, B. bigemina, e B. bovis, uma vez que a maioria dos animais foi soronegativa para pelo menos um dos agentes.Palavras-chave: Anaplasma marginale, Babesia bigemina, Babesia bovis, bovino, fatores de risco, Brasil.

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Bovine Trypanosomiasis in Brazil

Melo

Oliveira

Abreu-Silva

2017

Emerging and Re-Emerging Infectious Diseases of Livestock

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Aspectos clínicos, epidemiológicos e patológicos da infecção natural em bovinos por Trypanosoma vivax na Paraíba

Cited by 54 publications

References 16 publications

Evaluation of clinical signs, parasitemia, hematologic and biochemical changes in cattle experimentally infected with Trypanosoma vivax

Evaluation of clinical signs, parasitemia, hematologic and biochemical changes in cattle experimentally infected with Trypanosoma vivax

Seroprevalence and risk factors for cattle anaplasmosis, babesiosis, and trypanosomiasis in a Brazilian semiarid region

Bovine Trypanosomiasis in Brazil

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