In this study the influence of cell tilting on flow dynamics and heat transport is explored experimentally within a rectangular cell (aspect ratios Γ x = 1 and Γ y = 0.25). The measurements are carried out over a wide range of tilt angles (0 β π/2 rad) at a constant Prandtl number (Pr 6.3) and Rayleigh number (Ra 4.42 × 10 9 ). The velocity measurements reveal that the large-scale circulation (LSC) is sensitive to the symmetry of the system. In the level case, the high-velocity band of the LSC concentrates at about a quarter of the cell width from the boundary. As the cell is slightly tilted (β 0.04 rad), the position of the high-velocity band quickly moves towards the boundary. With increasing β, the LSC changes gradually from oblique ellipse-like to square-like, and other more complicated patterns. Oscillations have been found in the temperature and velocity fields for almost all β, and are strongest at around β 0.48 rad. As β increases, the Reynolds number (Re) initially also increases, until it reaches its maximum at the transition angle β = 0.15 rad, after which it gradually decreases. The cell tilting causes a pronounced reduction of the Nusselt number (Nu). As β increases from 0 to 0.15, 1.05 and π/2 rad, the reduction of Nu is approximately 1.4 %, 5 % and 18 %, respectively. Over the ranges of 0 β 0.15 rad, 0.15 β 1.05 rad and 1.05 β π/2 rad, the decay slopes are 8.57 × 10 −2 , 3.27 × 10 −2 and 0.24 rad −1 , respectively.