Aspect d´ovaire intra-utérin d´une môle partielle

Abstract

The study involved a 28-year-old female patient with no particular past medical history. At 7 weeks of amenorrhea, she presented at the Gynecological Emergency Department with pelvic pain. Clinical examination showed good general condition; vaginal examination objectified that the cervix was very far back (posterior), closed, without metrorrhagias or latero-uterine mass. Ultrasound showed fetal cardiac activity and all around the sac several “lacunae” (empty spaces) without leakage of fluid. Molar pregnancy was suspected based on image examination; hCG level was 37920 UI. The diagnosis of embryonated mole was evoked and complementary thoraco-abdominopelvic CT scan was performed to support the diagnosis and as staging evaluation. This showed partial hydatiform mole without signs of loco-regional or remote extension, with anterior intrauterine myoma. Ultrasound-guided aspiration was performed after availability of blood supply. During aspiration, vescicles were observed. Anatomo-pathological examination initially showed interrupted pregnancy with no chorionic villi. Given the strong suspicion of molar pregnancy, multiple sections were performed which showed rare large chorionic villi with edematous axis. These rare villi were lined with trophoblastic coverage of usual abundance and morphology, suggesting partial mole. The woman received effective contraception with weekly monitoring of BHCG levels. She was monitored until she experienced negative results from three consecutive tests (A, B, C, D).