“…Lymphovascular invasion (LVI) refers to the invasion of the tumor into lymphatic and/or blood vessels and acts as an important route for the local metastasis [ 3 ]. Regional LVI is closely associated with the recurrence of GC and the prognosis of GC patients, and LVI-positive patients have a higher recurrence rate and a worse 5-year survival rate [ 4 , 5 ]. Currently, GC patients are primarily stratified based on the TNM staging.…”