Asimicin, a New Cytotoxic and Pesticidal Acetogenin from the Pawpaw, Asimina triloba (Annonaceae)

Rupprecht, J. K.; Chang, Ching-Jer; Cassady, John M.; McLaughlin, Jerry L.

doi:10.3987/r-1986-05-1197

Cited by 77 publications

(2 citation statements)

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“…A. triloba leaf essential oil has strong activity against cancer cell lines ( Alali et al, 1999;Farag, 2009). A. triloba fruit, leaf, bark, and twig extract may be an effective insect feeding deterrent (Rupprecht et al, 1986;Ratnayake et al, 1992;Zhao et al, 1994;Gu et al, 1999;Sedlacek et al, 2010).…”

Section: Studies Of the Chemical Composition Of Fruits And Seeds Of Pawpaw (Asimina Triloba (L) Dunal)mentioning

confidence: 99%

Studies of the Chemical Composition of Fruits and Seeds of Pawpaw (Asimina triloba (L.) Dunal)

2021

Agrobiodivers Improv Nutr health life Qual

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An international team of scientists continues to study the resource potential of non-conventional or little-utilized plants. Pawpaw (Asimina triloba (L.) Dunal) fruit (pulp and peel) and seeds were analyzed for their nutritional compositions. Seeds exhibited significantly higher levels of crude protein, lipid, and vitamin E (11.82 %, 34.0 %, and 20.80 mg/kg, respectively) than those of the other parts. Sucrose in pulp was 501.40 g/kg, which was the highest among the samples. There is more fructose in the peel 111.90 g/kg. Results revealed that the total amino acids in the seeds, pulp, and peel of A. triloba were 144.6, 21.1, and 20.9 g/kg, respectively. Among the different plant parts used in this study, the seeds contained the most abundant essential amino acid and non-essential amino acid. The glutamic acid exhibited the highest concentration among the tested amino acids. Oleic and linoleic acids in seeds were 40.13 and 38.84 g/100 g, respectively, which were the highest among the pulp and peel. Potassium was the most abundant essential trace mineral element in different parts. This element is present in large ammounts in the peel (15487 mg/kg) and pulp (12198 mg/kg) compared to the seeds (3888 mg/kg). In the seeds, P, Ca and S were higher (1937, 1368, and 1322 mg/kg, respectively) than in pulp and peel (1046, 450, 499 and 831, 837, 646 mg/kg, respectively). The high content of beneficial substances makes it possible to include Asimina triloba in the list of species recommended for cultivation on a larger scale and to use its products more widely in dietary nutrition.

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Section: Studies Of the Chemical Composition Of Fruits And Seeds Of Pawpaw (Asimina Triloba (L) Dunal)mentioning

confidence: 99%

Studies of the Chemical Composition of Fruits and Seeds of Pawpaw (Asimina triloba (L.) Dunal)

2021

Agrobiodivers Improv Nutr health life Qual

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“…Dry matter and water content of the samples were determined by oven drying for 24 hours at 105 o C using a UN110 Memmert oven, method used also by Moura et al, (2005) with anticancerogenic and insecticidal properties (Johnson et al, 1996;Ratnayake et al, 1993;McLaughlin et al, 1986;Huang et al, 2003;Avula et al, 2018). Its habitus recommend it as an ornamental plant for landscapes, having special properties in air de-pollution (Szilagyi and Marian, 2011).…”

Section: Biochemical Analysesmentioning

confidence: 99%

Pawpaw Hybrid Genotypes (Asimina triloba (L.) Dunal) Cultivated in the Bucharest Area

et al. 2020

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Pawpaw or Northern banana (Asimina triloba (L.) Dunal) is the only representative of the Annonaceae family that can be cultivated in temperate areas. The increasing demands from the consumers for this nearly unknown fruit with high nutraceutical potential require specific researches. The aim of this study is to present the fruits pomological characteristics for 23 genotypes analyzed, cultivated in the Bucharest area. For each genotype yield, fruit size, average number of seeds per fruit, average weight of seeds and seeds size were measured. Fruit biochemical analyses as dry matter, total soluble solids, ascorbic acid content, acidity, were done for several genotypes. Fruit quality evaluation through sensorial analyses was conducted for 13 genotypes. The most valuable genotypes from the Experimental field according to the analyses performed and the consumer’s preferences are taken in consideration for further research.

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Total Syntheses of Squamocin A and Squamocin D, Bi-tetrahydrofuran Acetogenins from Annonaceae

Emde

Koert²

2000

Eur. J. Org. Chem.

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The total syntheses of the Annonaceous acetogenins squamocin A and squamocin D have been achieved. The synthesis follows a modular strategy, wherein a left‐side chain, the central bis‐THF core and the right‐side chain are assembled together. Key reactions are additions of organomagnesium compounds to bi‐THF aldehydes. At the end of the synthesis the butenolide moiety was introduced. This modular synthetic approach should be useful for the synthesis of other related natural products as well as pharmacologically interesting analogs.

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Asimicin, a New Cytotoxic and Pesticidal Acetogenin from the Pawpaw, Asimina triloba (Annonaceae)

Cited by 77 publications

References 0 publications

Studies of the Chemical Composition of Fruits and Seeds of Pawpaw (Asimina triloba (L.) Dunal)

Studies of the Chemical Composition of Fruits and Seeds of Pawpaw (Asimina triloba (L.) Dunal)

Pawpaw Hybrid Genotypes (Asimina triloba (L.) Dunal) Cultivated in the Bucharest Area

Total Syntheses of Squamocin A and Squamocin D, Bi-tetrahydrofuran Acetogenins from Annonaceae

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