Asian Versus Non-Asian Outcomes in Nasopharyngeal Carcinoma: A North American Population-based Analysis

Abstract

In this population-based study, Asian ethnicity was associated with improved DSS and OS. Concurrent chemoRT conferred more benefit among non-Asian compared with Asian subjects.

Survival differences in nasopharyngeal carcinoma among racial and ethnic minority groups in the United States: A retrospective cohort study

“…Our finding that non‐Hispanic Asians/Pacific Islanders had the highest disease‐specific of any other race/ethnicity has been reported previously but these studies mostly compared them with the White population in the United States . In our study, we compared rates to other minority populations, and the results remained the same as those previously published.…”

“…In our study, we compared rates to other minority populations, and the results remained the same as those previously published. Possible explanation for this favourable prognosis among non‐Hispanic Asians/Pacific Islanders suggested in the literature include younger age at diagnosis, Chinese ethnicity and genetics . Undifferentiated nonkeratinising histology (formerly known as the World Health Organisation (WHO) type III) may also contribute to the favourable prognosis in this race group .…”

Nasopharyngeal carcinoma: A review

“…77 The overall incidence of NPC was significantly more common in Asians than in Caucasians. The Asians had a predominance of NK histology (90%), and among Caucasians, NK-NPC was present in 57%.…”

Impact of age on survival of locoregional nasopharyngeal carcinoma: An analysis of the Surveillance, Epidemiology, and End Results program database, 2004‐2013

“…NPC has also been linked to infection with human papilloma virus (HPV), but co‐infection is common in high‐incidence regions such as Southeast Asia . Analysis of multi‐ethnic patient populations in North America has revealed that Asian patients tend to be diagnosed with keratinising squamous cell carcinoma (type I NPC) at significantly lower rates than do white, black, or Hispanic patients . Among Asian patient populations in high‐incidence regions, the rate of diagnosis of type IIb (non‐keratinising undifferentiated) NPC is frequently greater than 90% .…”