Aseptic HLA B27-positive spondylodiscitis: decreased 18F-FDG uptake after etanercept treatment

Benucci, Maurizio; Damiani, Arianna; Arena, A; Infantino, María; Manfredi, Michael A.; Gobbi, Francesca Li

doi:10.4081/reumatismo.2016.911

Cited by 2 publications

(1 citation statement)

References 2 publications

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“…It has to be reminded that FDG is not tumour or infective specific [ 69 , 70 ], and it could help in the identification of the right site for biopsy [ 71 , 72 ]. It has to be mentioned that FDG uptake was found in inflammatory and rheumatologic diseases [ 73 , 74 ], such as aseptic spondylodiscitis in a patient with HLA-B27 positive patient [ 74 ]. We always have to remember that FDG is not specific for the presence of microorganism, but the presence of our immune system reaction to external offences and increased metabolism cells, such as tumoral ones.…”

Section: Fdg Pet/ct Imagingmentioning

confidence: 99%

Spine Infections: The Role of Fluorodeoxyglucose Positron Emission Tomography (FDG PET) in the Context of the Actual Diagnosis Guideline

Boriani

Zamparini

Albrizio³

et al. 2022

CMIR

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: Spondylodiscitis is an infectious process which requires numerous health care professionals in order to be clearly diagnosed and eventually, successfully treated. It implies a variety of microbiological agents and condition; during the diagnostic workup it is difficult to correctly identify them, and the clinician has to rapidly choose the most correct treatment, in order to avoid permanent injuries to the patient. In this context it comes our review work: based on current guidelines and literature available we wanted to deeply understand the most proper use of Positron Emission Tomography with 18-Fluoro-deossi-glucose (FDG PET) in a patient with the suspect of spondylodiscitis. We wanted to review the role of FDG PET in the spondylodiscitis diagnosis and follow up in the context of the current guidelines.

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Section: Fdg Pet/ct Imagingmentioning

confidence: 99%

Spine Infections: The Role of Fluorodeoxyglucose Positron Emission Tomography (FDG PET) in the Context of the Actual Diagnosis Guideline

Boriani

Zamparini

Albrizio³

et al. 2022

CMIR

View full text Add to dashboard Cite

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Case reports: spondylodiscitis and epiduritis after suffering COVID-19

Ustenko

Kushnir

Амелин

et al. 2022

Journal of Clinical Practice

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Background. The review analyzes a possible rare complication of COVID-19 in the form of spondylodiscitis, including with developed epiduritis, in patients who have undergone COVID-19 with severe pneumonia, respiratory failure and systemic inflammatory response syndrome (SIRS). Clinical Case Description. Based on our own clinical observations, an approach to the diagnosis and treatment of three patients is described, each of whom had SIRS, severe fever, a significant increase in laboratory markers of inflammation (C - reactive protein (CRP), leukocytosis, erythrocyte sedimentation rate (ESR), fibrinogen, procalcitonin , ferretin), the addition of bacterial pneumonia, pronounced disorders of coagulation hemostasis, the development of spondylodiscitis, despite the wide range of previous antibiotic therapy, acute pain in the lumbar spine (LSP) with features of "red flags". In the first patient, against the background of massive antibiotic therapy, revisions of purulent foci, glucocorticosteroid (GCS) therapy, and surgical treatment, there was a significant positive trend in the form of pain relief. The second patient showed positive dynamics against the background of conservative antibiotic therapy. The third patient, with a paravertebral abscess at the level of developed spondylodiscitis, received massive antibiotic therapy in combination with GCS, and was operated on to decompress the spinal cord. Conclusion. The authors note that spondylodiscitis and epiduritis may be some of the possible complications of COVID-19 and / or the result of the unwanted action of drugs used to treat this disease. In this regard, timely diagnosis and treatment of this pathology in COVID - 19 seems to be very relevant

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Aseptic HLA B27-positive spondylodiscitis: decreased 18F-FDG uptake after etanercept treatment

Cited by 2 publications

References 2 publications

Spine Infections: The Role of Fluorodeoxyglucose Positron Emission Tomography (FDG PET) in the Context of the Actual Diagnosis Guideline

Spine Infections: The Role of Fluorodeoxyglucose Positron Emission Tomography (FDG PET) in the Context of the Actual Diagnosis Guideline

Case reports: spondylodiscitis and epiduritis after suffering COVID-19

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