Aseptic arthritis after gonorrhoea.

Rosenthal, L; Olhagen, B; Ek, Smith

doi:10.1136/ard.39.2.141

Cited by 39 publications

(9 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The triggering factors include enteric infections caused by Salmonella, Shigella, Campylobacter, and Yersinia enterocolitica, and urogenital infections caused by Chlamydia trachomatis (1) and, probably, Neisseria gonorrhoeae (2). Patients with Yersinia arthritis have a typical clinical picture that is common to other forms of reactive arthritis: inflammatory arthritis with a predilection for large weight-bearing joints, frequent extraarticular inflammatory signs, a 3-5-month self-limiting course of acute arthritis, and a high frequency of HLA-B27 (3).…”

Section: Ten-year Followup Study O F Patients Withmentioning

confidence: 99%

Ten‐year followup study of patients with yersinia arthritis

Leirisalo‐Repo

Suoranta

1988

Arthritis & Rheumatism

106

View full text Add to dashboard Cite

Eighty‐five patients with acute Yersinia arthritis were seen in followup for a mean of 10 years. During that time, peripheral joint symptoms occurred frequently (51.8%), but these symptoms were mild (45.9%). Development of a new reactive arthritis (4.7%) or chronic arthritis (2.4%) was uncommon. One‐third of the patients experienced low back pain, and one‐third of the patients had radiologic evidence of sacroiliitis. The presence of sacroiliitis was more frequent in patients with low back pain (46.7%) than in those who did not have symptoms (21.2%). More patients with HLA–B27 had low back pain and sacroiliitis, but there was no association of this genetic factor with the residual symptoms in peripheral joints.

show abstract

Section: Ten-year Followup Study O F Patients Withmentioning

confidence: 99%

Ten‐year followup study of patients with yersinia arthritis

Leirisalo‐Repo

Suoranta

1988

Arthritis & Rheumatism

106

View full text Add to dashboard Cite

show abstract

“…The early phase of gonococcal polyarthritis seems to occur as a form of reactive arthritis. By recent clinical and immunologic data, we may further confirm this kind of pathogenesis in the late aseptic arthritis that follows gonorrhea, which sometimes occurs as complete Reiter's syndrome in susceptible patients (i.e., in HLA-B27 individuals) (23).…”

Section: Discussionmentioning

confidence: 62%

Gonococcal arthritis–dermatitis syndrome. study of serum and synovial fluid immune complex levels

Manicourt

Orloff²

1982

Arthritis & Rheumatism

View full text Add to dashboard Cite

Immune complexes from serum and synovial fluid were detected by the Clq binding assay in 12 patients with disseminated gonococcal infection. Since immune complexes were regularly higher in synovial fluids than in paired sera and were not detected by the monoclonal rheumatoid factor radioimmunoassay, we suggest that IgM may be present in these complexes and that this represents a primary immune response. In contrast, only 2 of 10 patients with local gonococcal infection were slightly positive both with the Clq assay and the monoclonal rheumatoid factor assay. In patients with disseminated gonococcal infection, immune complexes closely paralleled the disease activity and negatively correlated with complement levels. Synovial fluid immune complexes seem to occur in the early and aseptic phase of polyarthritis and to aid the entrance of circulating gonococcal organisms. From the results of our study, it seems that immunologic processes initiate and/or sustain inflammation in disseminated gonococcal infections that appear, at least in part, as a form of reactive arthritis.Arthritis is a cardinal manifestation of disseminated gonococcal infection and is often the major From the Free University of Brussels, Belgium.

show abstract

“…in the joint [ 43 ]. (2) N. gonorrhoeae itself may induce an aseptic ReA in susceptible patients who are treated with penicillin early and adequately, allowing the gonococci to survive in the accessory glands or the oviducts; this hypothesis was suggested on the basis of similar clinical pattern compared with RS and greater lymphocyte stimulation induced by gonococcal antigen, which was more significant in patients with post-gonorrhoeal aseptic arthritis than in healthy controls [ 44 ]. (3) The antibiotic regime against gonococci does not simultaneously eradicate coincident chlamydial infection, which allows Chlamydia to invade the inflamed joint by dissemination from the urogenital reservoir.…”

Section: Aethiopathogenic and Clinical Implications Of Coinfectionmentioning

confidence: 99%

Coinfection of Chlamydiae and other Bacteria in Reactive Arthritis and Spondyloarthritis: Need for Future Research

Zeidler

Hudson

2016

Microorganisms

View full text Add to dashboard Cite

Reactive (inflammatory) arthritis has been known for many years to follow genital infection with the intracellular bacterial pathogen Chlamydia trachomatis in some individuals. Recent studies from several groups have demonstrated that a related bacterium, the respiratory pathogen Chlamydia pneumoniae, can elicit a similar arthritis. Studies of these organisms, and of a set of gastrointestinal pathogens also associated with engendering inflammatory arthritis, have been relatively extensive. However, reports focusing on coinfections with these and/or other organisms, and the effects of such coinfections on the host immune and other systems, have been rare. In this article, we review the extant data regarding infections by multiple pathogens in the joint as they relate to engendering arthritis, and we suggest a number of research areas that must be given a high priority if we are to understand, and therefore to treat in an effective manner, such arthritides.

show abstract

Aseptic arthritis after gonorrhoea.

Cited by 39 publications

References 18 publications

Ten‐year followup study of patients with yersinia arthritis

Ten‐year followup study of patients with yersinia arthritis

Gonococcal arthritis–dermatitis syndrome. study of serum and synovial fluid immune complex levels

Coinfection of Chlamydiae and other Bacteria in Reactive Arthritis and Spondyloarthritis: Need for Future Research

Contact Info

Product

Resources

About