2004
DOI: 10.1016/j.jep.2004.02.018
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Ascaridole-less infusions of Chenopodium ambrosioides contain a nematocide(s) that is(are) not toxic to mammalian smooth muscle

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Cited by 70 publications
(42 citation statements)
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References 19 publications
(34 reference statements)
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“…Then attention is necessary for the doses of leaf and inflorescence extracts. In our study a peculiarity was observed, C. ambrosioides was the species most used by the population, perhaps due to its popularity, its apparent effectiveness, low cost and easy availability (MacDonald et al 2004).…”
Section: Discussionmentioning
confidence: 67%
“…Then attention is necessary for the doses of leaf and inflorescence extracts. In our study a peculiarity was observed, C. ambrosioides was the species most used by the population, perhaps due to its popularity, its apparent effectiveness, low cost and easy availability (MacDonald et al 2004).…”
Section: Discussionmentioning
confidence: 67%
“…No entanto, este óleo não tem sido freqüentemente utilizado na medicina humana, devido a sua toxicidade para mamíferos (Macdonald et al, 2004;Silva, 2012). As propriedades biológicas do mastruz vêm, no entanto, sendo investigadas em extratos da planta, incluindo o extrato aquoso (Almeida et al, 2007;Silva, 2012).…”
Section: Resultsunclassified
“…As propriedades biológicas do mastruz vêm, no entanto, sendo investigadas em extratos da planta, incluindo o extrato aquoso (Almeida et al, 2007;Silva, 2012). Resultados de estudo in vitro demonstram que tanto o ascaridol, quanto a infusão das folhas isentas de ascaridol, apresentaram atividade anti-helmíntica, sugerindo que possivelmente, outros constituintes presentes na planta, que não o ascaridol, mas sim componentes hidrofílicos também estejam relacionados com esta atividade (MacDonald et al, 2004;Silva, 2012).…”
Section: Resultsunclassified
“…Ascaridole is one of the most important constituents of C. ambrosioides which is maximum in the seeds as compared to other parts. Some other phytoconstituents are also present in C. ambrosioides and those are ascaridole-glycol, α-pinene, myrcene, limonene, trans-pinocarveol, α-terpineol aritasone and phellandrene [2,4]. Different species of Leishmania cause cutaneous ulcers which affect a large number of populations in the world and native people are using Chenopodium oil for the treatment of some disorders.…”
Section: Biological Activities Of C Ambrosioidesmentioning
confidence: 99%
“…Ascaridole produces hypothermia and decreases locomotory activity in mice but at high dose level it is lethal for animals. Effect of ascaridole against malaria was also investigated and was found to inhibit the growth of Plasmodium falciparum (P. falciparum) [2]. Ascaridole is also known as ascarisin or 1,4-epidioxy-p-menth-2-ene which is a bicyclic monoterpene.…”
Section: Introductionmentioning
confidence: 99%