Arztrechtliche und morphologische Aspekte einer t�dlichen Fruchtwasseraspiration

Althoff, H; Cremer, U

doi:10.1007/bf00201257

Cited by 2 publications

(1 citation statement)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A severe respiratory distress syndrome was also described after massive inhalation of uncontaminated amniotic fluid. Althoff and Cremer [11] reported an incidence of amniotic fluid aspiration (AFA)-related respiratory distress up to 9%; in a French study [12], the detected incidence was 1.5% with 10% mortality. Moreover, AFA was indicated as potential cause of death in many reports [9,[13][14][15].…”

Section: Introductionmentioning

confidence: 98%

Amniotic fluid aspiration in cases of SIDS

et al. 2009

View full text Add to dashboard Cite

The scope of this study was to evaluate the incidence and the eventual consequences of amniotic fluid aspiration (AFA) in cases of sudden infant death. Cases of sudden infant death syndrome (SIDS; n = 113: 39 females, 74 males; mean age 4.6 months) were compared to a control group of 39 cases of explained death (14 females, 25 males; mean age 5.6 months). In each case, sections of the lung stained with hematoxylin and eosin and with the immunohistochemical reaction 34BE12 specific for cytokeratins were available. The microscope slides were observed at x200 magnification and semi-quantitatively classified into four categories(-, +, ++, and +++). In both groups, rests of amniotic fluid could be observed up to the fourth month of life. The comparison between the two groups did not show any significant difference. In the SIDS group, immunohistochemical reactions with the antibodies CD68, MRP8, MRP14, 27E10, 25F9, CD3, CD20Cy, and CD45R0 were available for the lungs. Twelve cases with AFA were compared to a group of SIDS cases without AFA with similar age and pathological distribution to evaluate whether the presence of amniotic remnants induced inflammatory changes in the lungs. No differences emerged. This study shows that AFA is not a rare event. Even moderate to severe AFA does not necessary cause death. A correlation between AFA and SIDS could not be shown.

show abstract