“…1) reports have been produced on a variety of masked phosphate derivatives designed to act as membrane-soluble prodrugs of the bio-active phosphate forms (Freed et al, 1989;Farrow et el., 1990;McGuigan et al, 1990a,b,c;Henin et et., 1991;McGuigan et sl., 1991;McGuigan et et., 1992;Namane et el., 1992;Dessaux and Huynh-Dinh, 1993). It was noted that diaryl phosphates derived from AZT are potent inhibitors of viral replication in vitro, in Received 31 July, 1995;revised 1 September,1995;accepted 4 September, 1995.…”