Artificial Receptors for the Recognition of Phosphorylated Molecules

Hargrove, Amanda E.; Nieto, Sonia; Zhang, Tianzhi; Sessler, Jonathan L.; Anslyn, Eric V.

doi:10.1021/cr100242s

Cited by 578 publications

(462 citation statements)

References 884 publications

(1,619 reference statements)

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“…In addition, the preparation of a few benzylic azides and diazides was carried out using an AER (N 3¯ form) in organic solvent mixtures such as CH 3 …”

Section: Discussionmentioning

confidence: 99%

Azolium-based systems: application of an anion exchange resin (A- form) method and 1H NMR analysis of the charged-assisted (C–H)+•anion hydrogen bonds

Dinarés¹,

Mesquida²,

Ibáñez³

et al. 2013

Arkivoc

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Dedicated to Prof. Rosa M. Claramunt on the occasion of her 65th birthday AbstractThe counteranion exchange of quaternary 1,2,3-triazolium salts was examined using a simple method that permitted halide ions to be swap for a variety of anions using an anion exchange resin (A¯ form). The method was applied to 1,2,3-triazolium-based ionic liquids and the iodideto-anion exchange proceeded in excellent to quantitative yields, concomitantly removing halide impurities. Additionally, an anion exchange resin (N 3¯ form) was used to obtain the benzyl azide from benzyl halide under mild reaction. Likewise, following a similar protocol, bis(azidomethyl)arenes were also synthesized in excellent yields. The results of a proton NMR spectroscopic study of simple azolium-based ion pairs are discussed, with attention focused on the significance of the charged-assisted (C-H) + ···anion hydrogen bonds of simple azolium systems such as 1-butyl-3-methylimidazolium and 1-benzyl-3-methyl-1,2,3-triazolium salts.

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“…In addition, the preparation of a few benzylic azides and diazides was carried out using an AER (N 3¯ form) in organic solvent mixtures such as CH 3 …”

Section: Discussionmentioning

confidence: 99%

Azolium-based systems: application of an anion exchange resin (A- form) method and 1H NMR analysis of the charged-assisted (C–H)+•anion hydrogen bonds

Dinarés¹,

Mesquida²,

Ibáñez³

et al. 2013

Arkivoc

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“…The binding of phosphate groups by nitrogen macrocycles and supramolecular receptors containing 2-6 nitrogen atom donors is certainly precedented [10], and there are literature examples of supramolecular phosphate receptors containing two methylated imidazolium groups that bind the H2PO4 -monoanion, shown in Figure 3 [11,12]. Hence we suggest that His-324/His-325 may sequester the phosphate monoanion of undecaprenyl phosphate, and activate it for nucleophilic attack on the phospho-enzyme intermediate.…”

mentioning

confidence: 76%

Inhibition of phospho-MurNAc-pentapeptide translocase (MraY) by nucleoside natural product antibiotics, bacteriophage ϕX174 lysis protein E, and cationic antibacterial peptides

Bugg

Rodolis

Mihalyi

et al. 2016

Bioorganic & Medicinal Chemistry

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“…Since the nucleotides, especially ATP is pivotal in living systems [38],numerous fluorescent chemosensors have been developed for their detection [39][40][41][42][43], involving direct sensing [44,45], cation-based recognition units [46][47][48][49][50][51][52] and also some indicator displacement assays [53][54][55][56][57].…”

Section: Introductionmentioning

confidence: 99%

Pillararene-based fluorescent indicator displacement assay for the selective recognition of ATP

Bojtár

Kozma

Szakács

et al. 2017

Sensors and Actuators B: Chemical

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Artificial Receptors for the Recognition of Phosphorylated Molecules

Cited by 578 publications

References 884 publications

Azolium-based systems: application of an anion exchange resin (A- form) method and 1H NMR analysis of the charged-assisted (C–H)+•anion hydrogen bonds

Azolium-based systems: application of an anion exchange resin (A- form) method and 1H NMR analysis of the charged-assisted (C–H)+•anion hydrogen bonds

Inhibition of phospho-MurNAc-pentapeptide translocase (MraY) by nucleoside natural product antibiotics, bacteriophage ϕX174 lysis protein E, and cationic antibacterial peptides

Pillararene-based fluorescent indicator displacement assay for the selective recognition of ATP

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