Artificial oocyte activation with Ca2+ ionophore improves reproductive outcomes in patients with fertilization failure and poor embryo development in the previous ICSI cycles
Abstract:Research question: Does artificial oocyte activation (AOA) by calcium ionophore (ionomycin) improve the previous fertilization failure or poor embryo development of intracytoplasmic sperm injection (ICSI) account for male factor infertility or other infertility causes?
Design: This retrospective study involved 114 patients receiving ICSI-AOA in Shanghai First Maternity and Infant Hospital from January 2019 to December 2020 with previous ICSI fertilization failure or poor embryo development. Thirty minutes afte… Show more
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