Artificial neural network analysis (ANNA) of prostatic transrectal ultrasound

Loch, Tillmann; Leuschner, Ivo; Genberg, Carl; Weichert-Jacobsen, K.; Küppers, Frank; Yfantis, Evangelos A.; Evans, Michael D.; Tsarev, Valeri; Stöckle, Michael

doi:10.1002/(sici)1097-0045(19990515)39:3<198::aid-pros8>3.3.co;2-o

Cited by 12 publications

(11 citation statements)

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“…Moreover, visual evaluation can give information about the distribution of EI within a muscle, i.e., homogeneous/inhomogeneous. New developments in quantification of muscle US, such as texture analysis, will also possibly be able to detect these alterations, as it has been able to detect focal changes in other imaging modalities with high sensitivity and specificity (such as breast and prostate sonograms) (Chen et al 2003;Loch et al 1999). Texture analysis has been investigated in skeletal muscle US of patients with NMD (Pohle et al 2000) and has been successful in adults in discriminating between neurogenic disorders and myopathies (Maurits et al 2003), but further investigations to evaluate the diagnostic value in children with various NMDs have to be done.…”

Section: Discussionmentioning

confidence: 99%

Skeletal muscle ultrasonography: Visual versus quantitative evaluation

Pillen

Keimpema²,

Nievelstein

et al. 2006

Ultrasound in Medicine & Biology

203

187

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Section: Discussionmentioning

confidence: 99%

Skeletal muscle ultrasonography: Visual versus quantitative evaluation

Pillen

Keimpema²,

Nievelstein

et al. 2006

Ultrasound in Medicine & Biology

203

187

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“…These include ultrasound (Doppler, contrast enhanced, tissue characterization algorithms) and MRI (contrast enhanced, diffusion weighted) but none have become standards of care to one or more issues with sensitivity, specificity, positive predictive value, negative predictive value, or reproducibility [17][18][19][20][21][22][23].…”

Section: Intraprostatic Imagingmentioning

confidence: 99%

Focal therapy for the treatment of localized prostate cancer

Ward¹,

Rewcastle

Ukimura

et al. 2012

Current Opinion in Urology

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“…Einerseits werden beim HistoScanning ungefilterte Signale ana lysiert und nach spezifischen Gewebee igenschaften ausgewertet [17]. Anderer seits wird beim CTRUS/ANNA die für die Abbildung des Bildes entscheidende Bildinformation ohne elektronische Ne bensignale genutzt [18]. Entscheidend er scheint hier, dass beim CTRUS/ANNA über 1000 bekannte und histopatholo gisch eindeutig klassifizierte Muster (Ge webedatenbank von radikalen Prostatek tomiepräparaten) als Basis für die Suche nach verdächtigen Arealen genutzt wer den [19].…”

Section: Innovative Urologische Bildgebungunclassified

“…Vorhergehende Studien an radi kalen Prostatektomiepräparaten, in denen die jeweiligen Ultraschalluntersuchungen mit den histologischen Befunden mit Hil fe einer artifiziellen neuronalen Netzwer kanalyse (ANNA) korreliert wurden, er möglichen diese Entwicklung[16,18,19].…”

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Zweimal negative Stanzbiopsie bei steigendem PSA

Loch

2010

Urologe

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In compliance with guidelines in cases of suspected prostate cancer, the standard approach involves transrectal ultrasound-guided systematic biopsies. Currently, according to the new S3 guideline for prostate cancer, 10-12 tissue samples should be collected per patient and session. If these primary specimens are negative, the number of multiple biopsies is generally increased in the second session to improve the diagnostic certainty with more biopsies. At the latest when the second core needle biopsy is performed in the presence of rising prostate-specific antigen (PSA) level, an attempt is made to minimize the risk of overlooking prostate cancer by further increasing the number of multiple biopsies in the sense of achieving saturation. In this instance, the number ranges from 6 to 143 tissue samples per session. Studies have provided evidence that after two systematic random biopsies the same number of additional random biopsies does not accomplish any essential improvement of diagnostic certainty. There are hardly any studies in the literature dealing with the role of imaging procedures after negative prostate biopsies. In a prospective clinical trial including 132 patients with an average of 12 negative previous biopsies, a dramatically high number of prostate carcinomas (66 of 132) could be detected with innovative imaging (1-6 targeted biopsies). This raises the question of how reliably multiple systematic biopsies can in fact exclude the presence of cancer. Thus, particularly after a negative series of multiple biopsies, it appears to be expedient to use specific imaging to enhance diagnostic certainty through quality. However, prospective clinical validation of the diverse innovative methods seems to be important before broad application.

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Artificial neural network analysis (ANNA) of prostatic transrectal ultrasound

Cited by 12 publications

References 0 publications

Skeletal muscle ultrasonography: Visual versus quantitative evaluation

Skeletal muscle ultrasonography: Visual versus quantitative evaluation

Focal therapy for the treatment of localized prostate cancer

Zweimal negative Stanzbiopsie bei steigendem PSA

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