Artificial intelligence and machine learning for early detection and diagnosis of colorectal cancer in sub-Saharan Africa

Waljee, Akbar K.; Weinheimer-Haus, Eileen; Abubakar, Amina; Ngugi, Anthony; Siwo, Geoffrey H.; Kwakye, Gifty; Singal, Amit G.; Rao, Arvind; Saini, Sameer D.; Read, Andrew J.; Baker, Jessica A.; Balis, Ulysses; Opio, Kenneth; Zhu, Ji; Saleh, Mansoor N.

doi:10.1136/gutjnl-2022-327211

Cited by 29 publications

(14 citation statements)

References 62 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…With the new trends in biotechnology and emerging health technologies such as artificial intelligence and data science [ 49 , 50 ], there is a need to develop competence for quality scientific and ethics review of complex protocols in Uganda [ 34 ], and for every high-volume REC in LMIC [ 35 ]. Bioethics education programs in SSA should broaden the scope of eligibility for higher-degree training in research ethics to keep up with the global demands of bioethics graduates.…”

Section: Discussionmentioning

confidence: 99%

Public health and research ethics education: the experience of developing a new cadre of bioethicists at a Ugandan institution

Kiwanuka,

Bajunirwe,

Alele

et al. 2024

BMC Med Educ

View full text Add to dashboard Cite

Research ethics education is critical to developing a culture of responsible conduct of research. Many countries in sub-Saharan Africa (SSA) have a high burden of infectious diseases like HIV and malaria; some, like Uganda, have recurring outbreaks. Coupled with the increase in non-communicable diseases, researchers have access to large populations to test new medications and vaccines. The need to develop multi-level capacity in research ethics in Uganda is still huge, being compounded by the high burden of disease and challenging public health issues. Only a few institutions in the SSA offer graduate training in research ethics, implying that the proposed ideal of each high-volume research ethics committee having at least one member with in-depth training in ethics is far from reality. Finding best practices for comparable situations and training requirements is challenging because there is currently no “gold standard” for teaching research ethics and little published information on curriculum and implementation strategies. The purpose of this paper is to describe a model of research ethics (RE) education as a track in an existing 2-year Master of Public Health (MPH) to provide training for developing specific applied learning skills to address contemporary and emerging needs for biomedical and public health research in a highly disease-burdened country. We describe our five-year experience in successful implementation of the MPH-RE program by the Mbarara University Research Ethics Education Program at Mbarara University of Science and Technology in southwestern Uganda. We used curriculum materials, applications to the program, post-training and external evaluations, and annual reports for this work. This model can be adapted and used elsewhere in developing countries with similar contexts. Establishing an interface between public health and research ethics requires integration of the two early in the delivery of the MPH-RE program to prevent a disconnect in knowledge between research methods provided by the MPH component of the MPH-RE program and for research in ethics that MPH-RE students are expected to perform for their dissertation. Promoting bioethics education, which is multi-disciplinary, in institutions where it is still “foreign” is challenging and necessitates supportive leadership at all institutional levels.

show abstract

Section: Discussionmentioning

confidence: 99%

Public health and research ethics education: the experience of developing a new cadre of bioethicists at a Ugandan institution

Kiwanuka,

Bajunirwe,

Alele

et al. 2024

BMC Med Educ

View full text Add to dashboard Cite

show abstract

“…It can also be altered and changed according to specific local needs. In the case of Sub-Saharan Africa, CRC screening is immensely difficult to perform on a large scale, due to a lack of endoscopists, pathologists, and the necessary chemical reagents needed to investigate biopsies [51].…”

Section: A Novel Approach To Crc Cancer Screening By Artificial Intel...mentioning

confidence: 99%

Colorectal cancer screening challenges in Saudi Arabia. A comprehensive review article

Zacharakis¹,

Almasoud²,

Aldossari³

2022

Arch Med Sci Civil Dis

View full text Add to dashboard Cite

Colorectal cancer (CRC) is the leading cause of cancer-related deaths in Saudi Arabia and usually presents late in patients, who become symptomatic in advanced stages; thus, most cases of CRC in Saudi Arabia have poor outcomes. Saudi Arabia currently follows published guidelines and recommends screening for CRC because early diagnosis is critical; the Saudi Arabian healthcare system runs a program "Colorecal Cancer Early Detection" that has been rolled out in a gradual fashion. A screening program would aim to find individuals with asymptomatic CRC, educate patients, and streamline the process of screening for medium-and high-risk people. Currently, the Saudi Arabian population present minimal knowledge regarding CRC, the benefits of screening, and the importance of regular screening. The Saudi population is heavily dependent on physician recommendations for CRC screening, but physicians working in primary healthcare rarely recommend screening for CRC even in patients who have risk factors. The screening program for CRC in Saudi Arabia is cost effective. Public education is necessary along with expanded colonoscopy resources to continue enhance citizen participation and overcome the barriers of CRC screening such as physician recommendation and female gender low participation.

show abstract

“…Unfortunately, according to the International Agency for Research on Cancer and the World Health Organization, the overall burden of CRC between 2020 and 2040 is expected to increase by about 56%, and the annual number of associated deaths by about 69% [ 6 ]. Furthermore, while it was thought to affect most countries that have adopted a western-type lifestyle, new studies suggest that CRC is an emerging public health issue even in other parts of the world, such as sub-Saharan Africa [ 8 ]. Therefore, early diagnosis and receiving proper treatment are necessary for the prevention of deaths caused by CRC.…”

Section: Introductionmentioning

confidence: 99%

The role of deep learning in diagnosing colorectal cancer

Bousis¹,

Verras²,

Bouchagier³

et al. 2023

View full text Add to dashboard Cite

Colon cancer is a major public health issue, affecting a growing number of individuals worldwide. Proper and early diagnosis of colon cancer is the necessary first step toward effective treatment and/or prevention of future disease relapse. Artificial intelligence and its subtypes, deep learning in particular, tend nowadays to have an expanding role in all fields of medicine, and diagnosing colon cancer is no exception. This report aims to summarize the entire application spectrum of deep learning in all diagnostic tests regarding colon cancer, from endoscopy and histologic examination to medical imaging and screening serologic tests.

show abstract

Artificial intelligence and machine learning for early detection and diagnosis of colorectal cancer in sub-Saharan Africa

Cited by 29 publications

References 62 publications

Public health and research ethics education: the experience of developing a new cadre of bioethicists at a Ugandan institution

Public health and research ethics education: the experience of developing a new cadre of bioethicists at a Ugandan institution

Colorectal cancer screening challenges in Saudi Arabia. A comprehensive review article

The role of deep learning in diagnosing colorectal cancer

Contact Info

Product

Resources

About