Arthroscopic Repair of Full-Thickness Tears of the Supraspinatus

Enhancement of rotator cuff tendon–bone healing using combined aligned electrospun fibrous membranes and kartogenin

“…The failure rate of tendon-bone healing aer RCT repair surgeries is still high because the brocartilage transition zone in tendon-bone enthesis is hard to regenerate. [2][3][4][5]47 The brocartilage transition zone can enhance the strength of tissue bonding between tendon and bone. In this study, local application of aligned PCL electrospun brous membranes improved brocartilage formation and collagen organization at the tendon-bone enthesis with the control group.…”

“…Despite the advancement of surgical treatments, the failure rates of rotator cuff repairs are still concerning to surgeons. [1][2][3][4][5][6] Previous clinical studies have demonstrated that tendon-bone healing is difficult to achieve. Tendon-bone junctions (TBJs) are unique structures composed of tendon, encalcied brocartilage, calcied brocartilage, and bone.…”

Characterization of tendon cell cultures of the human rotator cuff

“…Following surgical rotator cuff repairs, retear or nonhealing of the tendon is a relevant clinical problem (Boileau et al, 2005;Cole et al, 2007;Lafosse et al, 2007). Besides biomechanical improvements (Lorbach et al, 2008;Mahar et al, 2007;Pauly et al, 2010), recent approaches have suggested an influence of growth factors on tendon cell behaviour and their potential value in rotator cuff repair.…”

“…Although surgical approaches may provide good and excellent results in many patients (Severud et al, 2003;Wolf et al, 2004;Baysal et al, 2005), the main complication remains non-healing or retear of the tendon from its humeral footprint. Retears occur in up to 94% of cases and depend on several variable issues such as demographic factors, size of the initial tear, biologic characteristics (fatty infiltration, tendon tissue quality) and biomechanical aspects of the chosen surgical technique (Boileau et al, 2005;Bishop et al, 2006;Cole et al, 2007) The natural history of retears or recurrent defects remains unknown. The therapeutic aim of rotator cuff surgery represents a secure and durable tendon-to-bone regeneration.…”

Surgical Options for Failed Rotator Cuff Repair, except Arthroplasty: Review of Current Methods

“…Different studies have reported the rate of rotator cuff retear, in patients who underwent rotator cuff repair, to be between 11% and 94% [1][2][3][4][5][6][7][8][9]. Although the risk factors for retear are not clear, previous studies suggest older [4,10], preoperative big tear size [11,12], advanced degree of muscular atrophy [12], advanced degree of fatty infiltration [11,12], massive retraction of tendon [12,13], higher critical shoulder angle [14], lower acromiohumeral distance (AHD) [14], high tendon tension after repair, and inappropriate postoperative rehabilitation [12] as the major factors for failure of the rotator cuff repair. Management of patients with retear varies from conservative treatment to arthroplasty.…”