Arthroscopic Anterior Cruciate Ligament Reconstruction With at Least 2.5 Years' Follow-up Comparing Hamstring Tendon Autograft and Irradiated Allograft

Revision Rates After Anterior Cruciate Ligament Reconstruction Using Bone–Patellar Tendon–Bone Allograft or Autograft in a Population 25 Years Old and Younger

“…Allograft ACL reconstruction outcome reports have used hamstring 15,33,34 and BPTB allografts without reporting the type of processing used, 12,35 looked at all types of allografts, 7,25 or lumped all allografts together and failed to report the type of allograft used. [36][37][38] It cannot be assumed that all allografts are equivalent.…”

“…30 Gamma irradiation affects graft strength 5,31 and has been shown to result in higher failure rates. 14,15,32 Any study examining the differences between autograft and allograft ACL reconstruction must include information about the recovery and processing of the allografts. Different allograft studies cannot be assumed to be equivalent unless these critical differences in allograft processing are noted.…”

“…12 Harsh sterilization techniques 13 and higher doses of radiation are known to have a deleterious effect on allografts. 14,15 Patient selection is a key element in graft choice. A recent study reported no significant difference in function, activity, or satisfaction between allograft and autograft reconstructions in a younger patient population, although the allograft group had a much higher failure rate than the autograft group.…”

Allograft versus autograft for anterior cruciate ligament reconstruction: an up-to-date meta-analysis of prospective studies

“…Therefore, two prospective comparative studies with minimum two-year follow-up were excluded from this metaanalysis, due to involving the irradiated allografts [37,48]. Unfortunately, although we tried our best to contact the corresponding authors of those three studies that did not report the detail information of allografts, we still did not know the secondary sterilization methods of allografts in two included studies [43,44].…”

Anterior cruciate ligament reconstruction best practice: A review of graft choice

“…Similarly when comparing LARS to BTPB Pan et al [43] found no significant differences in functional outcome or examination findings between the two groups (30 BPTB and 32 LARS). In a large RCT of HS vs fresh frozen allograft with 7.8 year follow-up Sun et al [46] showed that apart from a shorter operative time for allograft procedures they showed no significant differences between the groups and both had similar outcome scores (IKDC 90 Allograft vs 89 Autograft). Interestingly they reported no ruptures and no complications apart from two superficial wound infections in the allograft group.…”