2010
DOI: 10.1093/rheumatology/keq264
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Arthritis in leprosy

Abstract: Leprosy, a chronic granulomatous infection caused by Mycobacterium leprae, classically presents with cutaneous and neurological manifestations. Musculoskeletal involvement though third most common is underdiagnosed and underreported. It may manifest in the form of Charcot's arthropathy, acute symmetrical polyarthritis or swollen hands and feet syndrome during lepra reactions, insidious-onset chronic symmetrical polyarthritis mimicking RA or as isolated tenosynovitis or tenosynovitis associated with arthritis o… Show more

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Cited by 76 publications
(93 citation statements)
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“…A study of 202 brucellar arthritis cases reported the involvement of the SI joint in 60.6% of cases. Furthermore, leprosy may also affect the SI, mimicking spondylarthropathy [25]. …”
Section: Discussionmentioning
confidence: 99%
“…A study of 202 brucellar arthritis cases reported the involvement of the SI joint in 60.6% of cases. Furthermore, leprosy may also affect the SI, mimicking spondylarthropathy [25]. …”
Section: Discussionmentioning
confidence: 99%
“…Other rheumatological manifestations occasionally reported are enthesitis, sacroiliitis, vasculitis, etc. [5859] Often, in lepromatous leprosy, antinuclear antibodies may also be weakly positive and may complicate the clinical picture. The authors have encountered Hansen's disease presenting with different clinical manifestations mimicking vasculitis, lupus, sarcoidosis, etc.…”
Section: Arthritis Associated With Infectionsmentioning
confidence: 99%
“…Rheumatological manifestations are seen in 1% to 70% of patients, resulting in clinical presentations of acute inflammatory arthritis, chronic symmetrical polyarthritis mimicking rheumatoid, Charcot's arthropathy, swollen hands and feet syndrome, tenosynovitis, vasculitis, lupus-like illness, and so forth [4, 5]. In addition various autoantibodies like antinuclear antibodies (ANA) and rheumatoid factor (RF) may be positive in leprosy, increasing the chances of misdiagnosis as a true autoimmune disease resulting in inappropriate treatment with immunosuppressive therapy [5]. …”
Section: Introductionmentioning
confidence: 99%