Arthritis-Dermatitis Syndrome: a Case of Disseminated Gonococcal Infection with Petechial Skin Rash

Blank, Jessica; Thapa, Namisha; Mansoor, André M.

doi:10.1007/s11606-021-06923-1

Cited by 7 publications

(5 citation statements)

References 9 publications

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“…Disseminated gonococcal infection is a medical emergency and its treatment should not be dependent on isolation of Neisseria gonorrhoeae, as laboratory tests may have low sensitivity. The case reinforces the importance of clinical diagnosis showing the triad, "tenosynovitis, polyarthralgia, and dermatitis" 1,2 . Early treatment prevents serious complications such as liver abscess, osteomyelitis, endocarditis, meningitis, and death 3 .…”

supporting

confidence: 66%

Disseminated gonococcal infection in an immunocompetent young man

Tavares

Victer

2022

Rev. Soc. Bras. Med. Trop.

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supporting

confidence: 66%

Disseminated gonococcal infection in an immunocompetent young man

Tavares

Victer

2022

Rev. Soc. Bras. Med. Trop.

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“…Differential diagnoses for patients presenting with polyarthralgia accompanied by fever encompass septic arthritis, reactive arthritis, rheumatoid arthritis, crystalline arthritis, seronegative spondyloarthropathy, and arthritis-dermatitis syndrome. Conditions that may present with a petechial rash with multisystem involvement include sepsis, meningococcemia, SLE, drug rash, and thrombocytopenia (Bank et al, 2021).…”

Section: Discussionmentioning

confidence: 99%

Difficult diagnosis: Disseminated gonorrheal infection manifesting as septic arthritis

Alleyne,

Mitchell

2024

J Am Assoc Nurse Pract

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Disseminated gonococcal infection is the causative agent of approximately 0.6%–1.2% of septic arthritis cases in North America and Europe. Typical presentations of this disorder include tenosynovitis, dermatitis, polyarthralgia, or oligoarticular purulent arthritis affecting the distal joints. Diagnosis is contingent on clinical presentation, with urine nucleic acid amplification testing as the preferred diagnostic modality. Synovial fluid cultures, along with imaging, can confirm diagnosis. The recommended treatment is a third-generation cephalosporin, such as intravenous ceftriaxone for 7–14 days and a dose of oral azithromycin.

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“…Gonorrhea is a sexually transmitted infection caused by N. gonorrhoeae with resultant genital infections, and rarely, pharyngeal and anorectal infections (6). Bacteremia resulting in DGI is found to be more common during pregnancy, menstruation, and with the use of intra-uterine devices (IUDs) (7) and seen in about 0.5-3% of the cases (8). Other risk factors predisposing for dissemination include homosexual or bisexual men, infection with resistant strains, and complement deficiencies (9).…”

Section: Discussionmentioning

confidence: 99%

Disseminated Gonococcal Infection with Dermatitis-Arthritis Syndrome

Humayun,

Bahadur,

Fatima

et al. 2023

Preprint

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Gonorrhea is a sexually transmitted infection caused by gram-negative diplococci, Neisseria gonorrhoeae . Disseminated gonorrhea is diagnosed infrequently, partly due to low suspicion at the time of presentation, and at times, due to overlapping symptoms associated with non-infectious conditions like systemic lupus erythematosus (SLE). In this article, we present a 42-year-old sexually active female with knee pain and swelling, fever, and rash. Knee aspirate showed the presence of monosodium urate crystals, and the synovial culture grew gram-negative diplococci, requiring multiple joint washouts. Urine nucleic acid amplification test (NAAT) was indeterminate. She was treated with high-dose intravenous ceftriaxone for 1 week post-joint washout with rapid improvement in her condition and resolution of the rash.

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Arthritis-Dermatitis Syndrome: a Case of Disseminated Gonococcal Infection with Petechial Skin Rash

Cited by 7 publications

References 9 publications

Disseminated gonococcal infection in an immunocompetent young man

Disseminated gonococcal infection in an immunocompetent young man

Difficult diagnosis: Disseminated gonorrheal infection manifesting as septic arthritis

Disseminated Gonococcal Infection with Dermatitis-Arthritis Syndrome

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