Arterial wall dynamics

Baltgaile, Galina

doi:10.1016/j.permed.2012.02.049

Cited by 26 publications

(18 citation statements)

References 29 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Hence, from our data, we found that cells in arterial beds with more capacity of distension present more stress fibers aligned. We could, again, extrapolate our findings considering that the blood flow shear stress play an important role in arterial distensibility (29). Thus, the cell stress fibers alignment may be a consequence of the shear stress.…”

Section: Resultssupporting

confidence: 67%

Quantification of alignment of vascular smooth muscle cells

et al. 2018

View full text Add to dashboard Cite

Vascular smooth muscle cells (VSMCs) are essential components that keep the tonus of the arterial network, which is the channel used to conduct the blood from the heart to the peripheral areas of the body. It is known that mechanical and architectural changes in VSMCs may lead to functional modifications in the cardiovascular system; therefore, the quantitative characterization of these changes can help to elucidate questions that remain unclear in pathological situations, such as hypertension, vasospasm, vascular hypertrophy, and atherosclerosis. In this work, we have developed a new framework of image processing using the Sobel operator, associated with statistical analysis, to determine the degree of local alignment of actin filaments, which we found to be directly related with the distensibility of the arterial wall. We have also compared these results with the rigidity of the cytoskeleton of VSMCs. The results suggest that the alignment degree increases from peripheral arteries, such as carotid and femoral, to central arteries, as well coronary and thoracic aorta, which can indicate that the level of local alignment of the actin fibers in VSMCs is related with the mechanical behavior of the arterial wall. © 2018 International Society for Advancement of Cytometry.

show abstract

Section: Resultssupporting

confidence: 67%

Quantification of alignment of vascular smooth muscle cells

et al. 2018

View full text Add to dashboard Cite

show abstract

“…Improvements in the segmentation and tracking processes may enable monitoring of even smaller vascular structures, potentially using a fully automated framework. The herein combination of precise ellipse fitting and 50 Hz temporal resolution further allowed observation of arterial wall dynamics, which have been identified as an independent risk factor for premature cardiovascular disease [14].…”

Section: Discussionmentioning

confidence: 99%

“…The fluctuations in the minor axis of the ellipse during each cardiac cycle determine the per-cycle diameter-based distensibility or wall strain (WS) of the artery over the periods before and after total occlusion (Eq. (1) [14]):…”

Section: Calculation Of Arterial Distensibility and Fmd Responsementioning

confidence: 99%

See 1 more Smart Citation

Flow-mediated dilatation test using optoacoustic imaging: a proof-of-concept

Karlas

Reber

Diot

et al. 2017

Biomed. Opt. Express

View full text Add to dashboard Cite

Label-free multispectral optoacoustic tomography (MSOT) has recently shown superior performance in visualizing the morphology of human vasculature, especially of smaller vessels, compared to ultrasonography. Herein, we extend these observations towards MSOT interrogation of macrovascular endothelial function. We employed a real-time handheld MSOT scanner to assess flow-mediated dilatation (FMD), a technique used to characterize endothelial function. A data processing scheme was developed to quantify the dimensions and diameter changes of arteries in humans and determine wall distensibility parameters. By enabling high-resolution delineation of the blood-vessel wall in a crosssectional fashion, the findings suggest MSOT as a capable alternative to ultrasonography for clinical FMD measurements.

show abstract

“…Новыми исследуемыми критериями в оценке аневризм ВОА стали растяжимость (distensibility, D) сосудистой стенки и комплайнс аорты (compliance, С), которые определяли по формулам [9]: Для количественных данных выполнялась проверка нормальности данных с помощью критерия Шапиро-Уилка. Распределение данных отличалось от нормального, в связи с чем данные описывали с помощью медианы, 25% и 75% квартилей.…”

Section: материал и методыunclassified

Assessment of the elastic properties of the ascending aorta using electrocardiographic synchronized computed tomography angiography with advanced data processing

et al. 2019

View full text Add to dashboard Cite

Aim. To modernize the computed tomography angiography (CTA) protocol with advanced data processing for the diagnosis of ascending aortic (AA) aneurysms, determining the aortic distensibility and compliance. Material and methods. We examined 24 patients (14 men) aged 43 to 72 years old with aneurysm or dilatation of ascending aorta (AA). CTA was performed on Siemens Somatom Definition AS and Philips Ingenuity Elite 128-slice scanners with electrocardiographic (ECG) synchronization after a bolus injection of contrast agents (100-120 ml). End-systolic and end-diastolic frames, maximum aortic diameter and cross-sectional area were determined; aortic distensibility and compliance were calculated.Results. According to AA diameter in end-diastolic frame, patients were divided into 3 groups. Group 1 — 6 patients, d< 45 mm (39 [39; 40] mm), group 2 — 7 patients, d =45-50 mm (48 [46; 49] mm) and group 3 — 11 patients, d >50 mm (51 [51; 54] mm). A correlation between aortic distensibility and compliance and such parameters as age, systolic blood pressure, systolic and was found. Correlation between the aortic compliance and diastolic diameter can be used for predicting of diameter increase rate.Conclusion. The designed CTA protocol with advanced data processing allows evaluating the AA distensibility and compliance by the diameter and cross-sectional area in patients with AA dilatation. These criteria provide additional information about the aortic elastic properties and can be used for determining the management strategy.

show abstract

Arterial wall dynamics

Cited by 26 publications

References 29 publications

Quantification of alignment of vascular smooth muscle cells

Quantification of alignment of vascular smooth muscle cells

Flow-mediated dilatation test using optoacoustic imaging: a proof-of-concept

Assessment of the elastic properties of the ascending aorta using electrocardiographic synchronized computed tomography angiography with advanced data processing

Contact Info

Product

Resources

About