Arterial Vascular Hemodynamics

Owen, Cindy A.; Roberts, Megan

doi:10.1177/8756479307302338

Cited by 7 publications

(8 citation statements)

References 1 publication

(1 reference statement)

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“…Consequently, it is assumed that the positive frequencies in the spectrum are arterial flow and negative frequencies are venous flow, so a reversed arterial flow cannot be distinguished from the venous flow. Although retrograde arterial flows are commonly observed in arteries supplying territories of high vascular resistance such as muscles at rest, or in arteries downstream to an arterial stenosis 4 , they are not expected to be found in healthy retinas since they are caused by an abnormal downstream or upstream resistance to flow. However, the existence of human retinal arterial retrograde flow has been reported in cases of retinal vein occlusions based on fluorescein or indocyanine-green angiography imaging 5 – 7 .…”

Section: Introductionmentioning

confidence: 99%

Retinal blood flow reversal quantitatively monitored in out-of-plane vessels with laser Doppler holography

Puyo

Pâques

Atlan

2021

Sci Rep

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Laser Doppler holography is a planar blood flow imaging technique recently introduced in ophthalmology to image human retinal and choroidal blood flow non-invasively. Here we present a digital method based on the Doppler spectrum asymmetry that reveals the local direction of blood flow with respect to the optical axis in out-of-plane vessels. This directional information is overlaid on standard grayscale blood flow images to depict flow moving towards the camera in red and flow moving away from the camera in blue, as in ultrasound color Doppler imaging. We show that thanks to the strong contribution of backscattering to the Doppler spectrum in out-of-plane vessels, the local axial direction of blood flow can be revealed with a high temporal resolution, which enables us to evidence pathological blood flow reversals. We also demonstrate the use of optical Doppler spectrograms to quantitatively monitor retinal blood flow reversals.

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Section: Introductionmentioning

confidence: 99%

Retinal blood flow reversal quantitatively monitored in out-of-plane vessels with laser Doppler holography

Puyo

Pâques

Atlan

2021

Sci Rep

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“…Blood flow in a straight artery with near uniform diameters is generally considered to be close to laminar flow ( 22 ). Non-laminar flow in an artery can be observed when it becomes bifurcated, dilated, tortuous, downstream to a stenosis, or has an arteriovenous communication ( 23 ). It is believed that post-stenotic turbulence is related to post-stenotic dilation and wall shear stress ( 24 ).…”

Section: Discussionmentioning

confidence: 99%

Quantitative Evaluation of Post-stenotic Blood Flow Disturbance in Canine Femoral Artery Stenosis Model: An Early Experience With Vector Flow Imaging

Zhao¹,

Zheng²,

Wang³

et al. 2022

Front. Cardiovasc. Med.

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ObjectiveTo investigate the value of Vector Flow Imaging (V Flow) in the assessment of post-stenotic turbulence in the canine arterial stenosis model.Materials and MethodsCanine femoral artery stenosis models were established using ameroid constrictors in 12 beagle dogs. 50% and then 70% femoral artery stenoses were confirmed by selective femoral artery angiography. V Flow was used to measure femoral artery flow turbulence index (Tur) preoperatively as a baseline. After establishing of a 50% and then 70% stenoses, the Tur indices were recorded in the femoral artery at 1, 3, 5, 7, 9, 11, 13, 15, 17, and 19 mm distal to the stenosis.ResultsBaseline Tur indices of normal canine femoral arteries were <1% in 11 of 12 cases (91.7%). Distal to a 50% stenosis, the Tur index (>1%) was recorded in 83.3–100% cases between 1 and 9 mm, 41.7–58.3% between 11 and 17 mm, and 16.7% at 19 mm. For a 70% stenosis, the Tur index (>1%) occurred in 81.8–100% cases between 1 and 17 mm distal to the stenosis, and 63.6% at 19 mm. The Tur index peaked around 7 mm or 2.3 times of the initial vessel diameter (3 mm) downstream for a 50% stenosis and 11 mm or 3.7 times of vessel diameter downstream for a 70% stenosis.ConclusionV Flow with Tur index measurement adds quantitative information of post-stenotic turbulence when assessing an arterial stenosis with ultrasound. Tur index of 1% seems a useful threshold for assessment of flow turbulence in this small sample study. Further studies with larger sample size are needed to evaluate the value of V Flow in clinical applications.

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“…Arterial retrograde flow is commonly observed with Doppler ultrasound in arteries supplying territories of high vascular resistance such as muscles at rest, or in arteries downstream to an arterial stenosis [21]. In ophthalmic applications of Doppler ultrasound, arterial blood flow reversal has been observed in the ophthalmic artery in cases of severe occlusive carotid artery [22,23], but to our knowledge it has not been reported in the central retinal artery.…”

Section: Discussionmentioning

confidence: 93%

Retinal blood flow reversal quantitatively monitored in out-of-plane vessels with laser Doppler holography

Puyo¹,

Pâques²,

Atlan³

2020

Preprint

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Laser Doppler holography is a planar blood flow imaging technique recently introduced in ophthalmology. We here present a digital method to reveal the local direction of blood flow with respect to the optical axis based on the Doppler spectrum asymmetry. This directional information is overlaid on standard grayscale blood flow images to depict flow towards the camera in red, and flow away from the camera in blue. The local axial direction of blood flow can be revealed with a high temporal resolution allowing to evidence potential blood flow reversal in out-of-plane retinal vessels. Spectrograms can also be advantageously used to visualize the axial direction of blood flow and perform quantitative blood velocity measurements.

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Arterial Vascular Hemodynamics

Cited by 7 publications

References 1 publication

Retinal blood flow reversal quantitatively monitored in out-of-plane vessels with laser Doppler holography

Retinal blood flow reversal quantitatively monitored in out-of-plane vessels with laser Doppler holography

Quantitative Evaluation of Post-stenotic Blood Flow Disturbance in Canine Femoral Artery Stenosis Model: An Early Experience With Vector Flow Imaging

Retinal blood flow reversal quantitatively monitored in out-of-plane vessels with laser Doppler holography

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