Objective: Roadmap fluoroscopy has never previously been
evaluated for axillary vein puncture in clinical practice. Our
retrospective cohort study was performed to investigate the efficacy and
safety of axillary vein puncture real-time guided by roadmap fluoroscopy
in cardiac pacemaker implantation. Methods and Results: A total
of 178 patients undergoing axillary vein puncture in permanent pacemaker
implantation were included in the present cohort study during a 1-year
period at our institution. All procedures were performed by the
operators with previous experience in axillary approach. Primary
endpoint was defined as axillary vein success rate. Secondary endpoints
were venous access site change, time to obtain venous access, procedural
time, and complication rate. For the primary outcomes, a higher success
rate was observed in the roadmap group compared with the blind puncture
group (95.2% vs 78.7%; P<0.001), as well as a lower
rate of venous access site change (7.1% vs 35.1%; P
<0.001) and shorter time to obtain venous access and
procedural time, with lower complications (3.6 % vs 6.4 %;
P<0.01). Conclusion: The roadmap fluoroscopy
real-time guided axillary venous access is safer and has a better
success rate and faster execution time compared with the blind axillary
puncture in cardiac pacemaker implantation. However, further larger
scale prospective randomized controlled trials are required to confirm
the findings.