2012
DOI: 10.1016/j.ultras.2011.09.006
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Arterial stiffness identification of the human carotid artery using the stress–strain relationship in vivo

Abstract: Arterial stiffness is well accepted as a reliable indicator of arterial disease. Increase in carotid arterial stiffness has been associated with carotid arterial disease, e.g., atherosclerotic plaque, thrombosis, stenosis, etc. Several methods for carotid arterial stiffness assessments have been proposed. In this study, in-vivo noninvasive assessment using applanation tonometry and an ultrasound-based motion estimation technique was applied in seven healthy volunteers (age 28 ± 3.6 years old) to determine pres… Show more

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Cited by 132 publications
(115 citation statements)
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“…This is because the wave arrival time can be tracked as long as the displacement contains an axial component, which will be the case as long as the probe is not completely parallel to the vessel. This feature of PWI has been confirmed in successful applications of the technique in humans with clinically available equipment (20,32,33). Hence, the metrics of aneurysm stability proposed in this study are also angle independent and robust to changes in the field of view, which are important features for clinical practice.…”
Section: Experimental Studies: Assessing the Stability Of Aortic Aneusupporting
confidence: 65%
“…This is because the wave arrival time can be tracked as long as the displacement contains an axial component, which will be the case as long as the probe is not completely parallel to the vessel. This feature of PWI has been confirmed in successful applications of the technique in humans with clinically available equipment (20,32,33). Hence, the metrics of aneurysm stability proposed in this study are also angle independent and robust to changes in the field of view, which are important features for clinical practice.…”
Section: Experimental Studies: Assessing the Stability Of Aortic Aneusupporting
confidence: 65%
“…timated to have Young's moduli of 700 to 900 kPa in vivo (31,32). Endothelial cells plated on collagen-coated polyacrylamide hydrogels demonstrated progressive flattening and proliferation rates on matrix beds with Young's moduli of between 13.6 and 95.1 kPa in addition to essentially nondeformable plastic (Fig.…”
Section: Fig 5 P66mentioning
confidence: 98%
“…The silicone tubing was 3 mm in outer diameter and 0.5 mm in thickness. Young' s moduli of the arteries range in value from 1 to 9 MPa in the literature (Gao, et al, 2006), (Horiuchi, et al, 2012), (Hučko, 2010), (Khamdaeng, et al, 2012). The static Young' s modulus of the silicone tubing used was about 4 MPa and the hardness was 56 Shore A.…”
Section: Methodsmentioning
confidence: 99%