Arterial stiffness and sedentary lifestyle: Role of oxidative stress

Lessiani, Gianfranco; Santilli, Francesca; Boccatonda, Andrea; Iodice, Pierpaolo; Liani, Rossella; Tripaldi, Romina; Saggini, Raoul; Davı̀, Giovanni

doi:10.1016/j.vph.2015.05.017

Cited by 48 publications

(29 citation statements)

References 51 publications

(61 reference statements)

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“…These findings are consistent with Kato et al (17) results and these alterations can be explained by the effect of nicotine on these parameters.…”

Section: Discussionsupporting

confidence: 93%

See 1 more Smart Citation

Effects of Varenicline on Cardiovascular Parameters and Oxidative Stress

Sarıoğlu¹,

Erken²,

Ayhan³

et al. 2017

Eurasian J Pulmonol

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“…These findings are consistent with Kato et al (17) results and these alterations can be explained by the effect of nicotine on these parameters.…”

Section: Discussionsupporting

confidence: 93%

“…Oxidative stress is believed to be closely associated with arterial stiffness (17). A recent study suggested that one possible mechanism for arterial stiffness is the imbalance between oxidative stress and total antioxidant status (TAS) (18).…”

mentioning

confidence: 99%

Effects of Varenicline on Cardiovascular Parameters and Oxidative Stress

Sarıoğlu¹,

Erken²,

Ayhan³

et al. 2017

Eurasian J Pulmonol

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“…Epidemiological, observational and intervention studies indicate that exercising can reduce the risk of neurodegenerative diseases (e.g., dementia [2,4,77], multiple sclerosis [78], Parkinson's disease [79,80]). Proposed mechanisms of exercise induced neuroplasticity are increased expression, secretion, and downstream signaling of neurotrophic factors (e.g., BDNF, VEGF, IGF-1), reduced inflammation [81,82], reduced stress levels [83] and improved cardiovascular (e.g., reduced arterial stiffness, reduced blood pressure) [84,85] and metabolic (e.g., insulin sensitivity) [86,87] parameters. Numerous studies have shown that exercise induced neuroplasticity is associated with BDNF [88,89].…”

Section: Physical Exercise and Bdnfmentioning

confidence: 99%

Lactate and BDNF: Key Mediators of Exercise Induced Neuroplasticity?

Müller

Duderstadt

Leßmann

et al. 2020

JCM

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Accumulating evidence from animal and human studies supports the notion that physical exercise can enhance neuroplasticity and thus reduce the risk of several neurodegenerative diseases (e.g., dementia). However, the underlying neurobiological mechanisms of exercise induced neuroplasticity are still largely unknown. One potential mediator of exercise effects is the neurotrophin BDNF, which enhances neuroplasticity via different pathways (e.g., synaptogenesis, neurogenesis, long-term potentiation). Current research has shown that (i) increased peripheral lactate levels (following high intensity exercise) are associated with increased peripheral BDNF levels, (ii) lactate infusion at rest can increase peripheral and central BDNF levels and (iii) lactate plays a very complex role in the brain’s metabolism. In this review, we summarize the role and relationship of lactate and BDNF in exercise induced neuroplasticity.

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“…A study by Lessiani et al showed that exercise training was significantly associated with markers of lipid peroxidation; also PWV was significantly reduced after this exercise. They concluded that regular physical exercise may be a natural antioxidant strategy, lowering oxidant stress and thereby the degree of arterial stiffness 46 .…”

Section: C-reactive Proteinmentioning

confidence: 99%

Pulse wave analysis and diabetes mellitus. A systematic review

et al. 2017

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Cardiovascular (CV) disease is the primary cause of death in diabetic patients and one of the explanations may be increased arterial stiffness. Arterial stiffness assessment using pulse wave analysis, is a predictive factor of CV events. The aim of this paper is to review the current knowledge of relations between diabetes mellitus and pulse wave analysis. A MEDLINE search was performed to retrieve both original and review articles addressing the relations and influences on arterial stiffness in diabetics. Pulse wave analysis is considered as a gold standard in CV risk evaluation for patients at risk, especially diabetics. Arterial stiffness assessment may be helpful for choosing more aggressive diagnostic and therapeutic strategies, particularly in younger patients to reduce the incidence of CV disease in these patients.

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Arterial stiffness and sedentary lifestyle: Role of oxidative stress

Cited by 48 publications

References 51 publications

Effects of Varenicline on Cardiovascular Parameters and Oxidative Stress

Effects of Varenicline on Cardiovascular Parameters and Oxidative Stress

Lactate and BDNF: Key Mediators of Exercise Induced Neuroplasticity?

Pulse wave analysis and diabetes mellitus. A systematic review

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