Arterial stiffness: a possible predictor of atrial fibrillation

Farina, Giovani Schulte; Kalil, Carlos; Gutiérrez, Jose Plutarco; Barbosa, Eduardo

doi:10.31083/j.rcm2301032

Cited by 3 publications

(1 citation statement)

References 50 publications

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“…Atrial fibrillation (AF) is one of the most common cardiac arrhythmias worldwide [ 1 , 2 ]. The risk of stroke, heart failure, and even cardiac death in patients with AF is significantly increased, thus severely impacting their quality of life and causing financial burden [ 3 , 4 ].…”

Section: Introductionmentioning

confidence: 99%

Predictors of Low Voltage Zone and Sex Differences in Low Voltage Zone Distribution in Patients with Atrial Fibrillation

Xin,

Hang,

2023

Rev. Cardiovasc. Med.

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Background: Previous studies have revealed the left atrial (LA) low voltage zone (LVZ) are tightly linked to the recurrence of atrial fibrillation (AF). Furthermore ablation that targets the LA LVZ can improve patient prognosis. The aim of this study was to identify potential clinical predictors of the LA LVZ, to investigate possible sex differences in the distribution of LA LVZ, and to examine the relationship between LA LVZ and AF recurrence. Methods: A total of 108 patients who underwent AF catheter ablation and LA high-density electro-anatomic mapping were enrolled in the study. Of these, 56 patients with LA LVZ 5% were assigned to the LVZ group, while the remaining 52 patients with LA LVZ 5% were assigned to the non-LVZ group. Clinical characteristics and laboratory results for all patients were collected and compared between the two groups. Results: Multivariate logistic regression analysis revealed that persistent AF (odds ratio [OR] = 4.563, 95% confidence interval [CI]: 1.194–17.431, p = 0.026), left atrial volume (LAV, OR = 1.030, 95% CI: 1.001–1.061, p = 0.044) and brain natriuretic peptide (BNP, OR = 1.010, 95% CI: 1.002–1.019, p = 0.015) were independent predictors for the presence of LA LVZ. In addition, female sex (OR = 7.161, 95% CI: 1.518–33.792, p = 0.013), LAV (OR = 1.028, 95% CI: 1.002–1.055, p = 0.035) and BNP (OR = 1.009, 95% CI: 1.001–1.016, p = 0.018) were independent predictors of severe LA LVZ (LA LVZ 20%). The extent of LVZ was significantly greater in females than in males (32.8% 15.5% vs . 23.5% 12.7%, p = 0.021), especially in the anterior (34.5% 16.7% vs . 20.0% 16.4%, p = 0.003) and septal (44.9% 17.1% vs . 29.0% 18.9%, p = 0.004) walls. During follow-up, AF recurrence was significantly higher in patients with LA LVZ than in those without LA LVZ (31.3% vs . 12.8%, respectively, p = 0.023). Conclusions: In this study cohort, persistent AF, LAV and BNP were independent predictors of LA LVZ. Furthermore, female sex, LAV and BNP were independent predictors of severe LA LVZ. Females had a significantly greater extent of LVZ than males, especially in the anterior and septal walls. Patients with LA LVZ had a higher risk of recurrent AF.

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Section: Introductionmentioning

confidence: 99%

Predictors of Low Voltage Zone and Sex Differences in Low Voltage Zone Distribution in Patients with Atrial Fibrillation

Xin,

Hang,

2023

Rev. Cardiovasc. Med.

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A Real-World Evaluation of Primary Medication Nonadherence in Patients with Nonvalvular Atrial Fibrillation Prescribed Oral Anticoagulants in the United States

Hernandez

Divino

Xie

et al. 2023

Am J Cardiovasc Drugs

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Predictive Value of Serum Lncrna MALAT1 for the Recurrence of Persistent Atrial Fibrillation After Radiofrequency Ablation

Chen,

Zhou,

Chen

et al. 2023

Biomark. Med.

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Objective: The authors investigated the predictive value of MALAT1 for persistent atrial fibrillation (PAF) recurrence after radiofrequency ablation. Methods: Serum MALAT1 level was determined. The correlation between MALAT1 and high-sensitivity C-reactive protein/left atrial diameter (LAD) was analyzed. The predictive value of MALAT1 was evaluated. The postoperative recurrence rate in patients with high/low MALAT1 was compared. Independent risk factors for postoperative recurrence were analyzed. Results: MALAT1 was elevated in PAF patients and positively correlated with high-sensitivity C-reactive protein/LAD. MALAT1/high-sensitivity C-reactive protein/LAD were enhanced in patients with recurrent PAF. Patients with high MALAT1 had a higher recurrence rate. Upregulated MALAT1 was an independent risk factor for postoperative PAF recurrence. Conclusion: Serum MALAT1 level >2.03 predicts postoperative recurrence of PAF, and PAF patients with high MALAT1 have a higher risk of postoperative recurrence.

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Arterial stiffness: a possible predictor of atrial fibrillation

Cited by 3 publications

References 50 publications

Predictors of Low Voltage Zone and Sex Differences in Low Voltage Zone Distribution in Patients with Atrial Fibrillation

Predictors of Low Voltage Zone and Sex Differences in Low Voltage Zone Distribution in Patients with Atrial Fibrillation

A Real-World Evaluation of Primary Medication Nonadherence in Patients with Nonvalvular Atrial Fibrillation Prescribed Oral Anticoagulants in the United States

Predictive Value of Serum Lncrna MALAT1 for the Recurrence of Persistent Atrial Fibrillation After Radiofrequency Ablation

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